Evidence map›Paper›PMID 36754054›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2023

DNA transposon mechanisms and pathways of genotoxicity.

Frederic D Bushman

Abstract read
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. ThebioRxiv : the preprint server for biology · 2025
    Article
  2. Review
  3. Response to: DNA transposon mechanisms and pathways of genotoxicity.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Frederic D BushmanDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: bushman@pennmedicine.upenn.edu.

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI DAVID S METZGER · 1999 to 2026
$78.6M
Modeling HIV CAR-T cell trafficking and persistence in Non-Human PrimatesU19AI149680 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI BUSHMAN, FREDERIC D · 2020 to 2024
$13.2M
Gene Therapy for SCID-X1 with Low Dose Busulfan and a SIN-lentiviral VectorU01AI125051 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI DAVID A WILLIAMS · 2016 to 2026
$9.7M
A Phase I Clinical Trial Testing Feasibility of Hematopoietic Stem Cell Gene Therapy Using Platelet Factor VIII to Safely Improve Hemostasis for Severe Hemophilia A with Inhibitory AntibodiesR01HL142791 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI EAPEN, MARY, WILCOX, DAVID ALLEN · 2019 to 2023
$8.2M
Linking insertional mutagenesis and cell function to improve CAR T cell therapyR01CA241762 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BUSHMAN, FREDERIC D, MELENHORST, JAN J · 2019 to 2023
$3.1M
NCI NIH HHS R01 CA241762NHLBI NIH HHS R01 HL142791NIAID NIH HHS P30 AI045008NIAID NIH HHS U01 AI125051NIAID NIH HHS U19 AI149680
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA DamageDNA Transposable ElementsDNA Transposable Elements

Identifiers

PMID36754054
PMCPMC10014265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.