Evidence map›Paper›PMID 36754025›Full record

ReviewPathobiology : journal of immunopathology, molecular and cellular biology2023

Guidelines for Handling of Cytological Specimens in Cancer Genomic Medicine.

Eiichi Morii, Yutaka Hatanaka, Noriko Motoi, Akihiko Kawahara, Shinji Hamakawa, Takeshi Kuwata, Tadasuke Nagatomo, Yoshinao Oda, Aikou Okamoto, Ryota Tanaka and 14 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pathobiology : journal of immunopathology, molecular and cellular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Next step of molecular pathology: next-generation sequencing in cytology.Journal of pathology and translational medicine · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Eiichi MoriiDepartment of Pathology, Osaka University, Suita, Japan.
Yutaka HatanakaResearch Division of Genome Companion Diagnostics, Hokkaido University Hospital, Sapporo, Japan.
Noriko MotoiDepartment of Pathology, Saitama Cancer Center, Saitama, Japan.
Akihiko KawaharaDepartment of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan.
Shinji HamakawaClinical Laboratories, Showa General Hospital, Tokyo, Japan.
Takeshi KuwataDepartment of Genetic Medicine, National Cancer Center Hospital East, Kashiwa, Japan.
Tadasuke NagatomoDepartment of Pathology, Osaka University, Suita, Japan.
Yoshinao OdaDepartment of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Aikou OkamotoDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Ryota TanakaDepartment of Surgery, Kyorin University School of Medicine, Mitaka, Japan.
Akira IyodaDivision of Chest Surgery, Department of Surgery, Toho University School of Medicine, Tokyo, Japan.
Maeda IchiroDepartment of Diagnostic Pathology, Kitasato University Kitasato Institute Hospital, Tokyo, Japan.
Yukiko MatsuoDepartment of Thoracic Surgery, Kitasato University School of Medicine, Sagamihara, Japan.
Nobuyuki NakamuraDepartment of Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Japan.
Tokiko NakaiDepartment of Diagnostic Pathology, Harima-Himeji General Medical Center, Himeji, Japan.
Mei FukuharaDepartment of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan.
Kazuya TokitaDepartment of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan.
Tomohiko YamaguchiDepartment of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Masataka TakenakaDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Ayako KawabataDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Kanako C HatanakaCenter for Development of Advanced Diagnostics, Hokkaido University Hospital, Sapporo, Japan.
Kaho TsubameCenter for Development of Advanced Diagnostics, Hokkaido University Hospital, Sapporo, Japan.
Yukitoshi SatohDepartment of Thoracic Surgery, Kitasato University School of Medicine, Sagamihara, Japan.
Working Group on Cytology in the Era of Genomic Medicine

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid advances are being made in cancer drug therapy. Since molecularly targeted therapy has been introduced, personalized medicine is being practiced, pathological tissue from malignant tumors obtained during routine practice is frequently used for genomic testing. Whereas cytological specimens fixed mainly in alcohol are considered to be more advantageous in terms of preservation of the nucleic acid quality and quantity. This article is aimed to share the information for the proper handling of cytological specimens in practice for genomic medicine based on the findings established in "Guidelines for Handling of Cytological Specimens in Cancer Genomic Medicine (in Japanese)" published by the Japanese Society of Clinical Cytology in 2021. The three-part practical guidelines are based on empirical data analyses; Part 1 describes general remarks on the use of cytological specimens in cancer genomic medicine, then Part 2 describes proper handling of cytological specimens, and Part 3 describes the empirical data related to handling of cytological specimens. The guidelines indicated proper handling of specimens in each fixation, preparation, and evaluation.

Indexed as

Genomic MedicineNeoplasmsCytodiagnosisHumansSpecimen HandlingCancer gene testingCancer genomic medicineCytologyGuidelineSample processing

Identifiers

PMID36754025
PMCPMC10627493

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.