ArticleScience translational medicine2023
Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria.
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Article in Science translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
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Who cites it
24 citing papers in PubMed, 25 citations in OpenAlex.
- NK cell cytotoxicity is transiently enhanced during acute malaria and modulated by the host microenvironment.JCI insight · 2026Article
- Predictive value of PfEMP1 antibody profiles for the course of controlled human malaria infections.PLoS pathogens · 2026Article
- Latent cytomegalovirus disrupts innate NK cell responses to P. falciparum and impairs parasite control in first infection in adults.PLoS pathogens · 2026Article
- Controlled human malaria infection in adults identify combinations of merozoite antigens associated with clinical immunity.Nature communications · 2026Article
- Accessing invasion-competent Plasmodium vivax merozoites reveals antibody-dependent NK cell activation.Research square · 2026Article
- Altered natural killer cell function in children with severe malaria.ImmunoHorizons · 2026Article
- Relationship between antibody avidity, Fc-mediated functional activity and longevity of malaria vaccine responses in clinical trials.Frontiers in immunology · 2026Article
- Reinventing malaria control: hierarchical intervention strategies for African settings based on the microbiota-barrier-innate immunity axis.Frontiers in immunology · 2026Review
- Full-length merozoite surface protein 1 formulated with GLA-SE adjuvant in malaria pre-exposed adults: a randomised, controlled, double-blind, parallel-group, single-centre Phase Ib trial.EClinicalMedicine · 2025Article
- Controlled human malaria infection studies: insights into recent advances and key immunological and ethical implementation lessons.Frontiers in immunology · 2025Review
- The impact of Plasmodium-driven immunoregulatory networks on immunity to malaria.Nature reviews. Immunology · 2024Review
- Full-length MSP1 is a major target of protective immunity after controlled human malaria infection.Life science alliance · 2024Article
- Breadth of Fc-mediated effector function correlates with clinical immunity following human malaria challenge.Immunity · 2024Article
- Risk of Malaria Following Untreated Subpatent Plasmodium falciparum Infections: Results Over 4 Years From a Cohort in a High-Transmission Area in Western Kenya.The Journal of infectious diseases · 2024Article
- Article
- Antibody-Dependent Respiratory Burst againstVaccines · 2024Article
- Natural killer cell antibody-dependent cellular cytotoxicity toClinical & translational immunology · 2024Article
- Bi-isotype immunoglobulins enhance antibody-mediated neutrophil activity againstFrontiers in immunology · 2024Article
- NK cells contribute to the resolution of experimental malaria-associated acute respiratory distress syndrome after antimalarial treatment.Frontiers in immunology · 2024Article
- Human transcriptional signature of protection afterHuman vaccines & immunotherapeutics · 2023Article
Corrections and comments
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Authors and funding
71 authors at 3 institutions in 4 countries.
Dennis O OderaCentre of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0003-4645-9637
James TujuCentre for Geographic Medicine Research (Coast), Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.ORCID 0000-0002-0624-1791
Kennedy MwaiCentre for Geographic Medicine Research (Coast), Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.ORCID 0000-0002-7757-7516
Irene N NkumamaCentre of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0002-2836-3001
Kristin FürleCentre of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0001-6835-3759
Timothy ChegeCentre for Geographic Medicine Research (Coast), Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.ORCID 0000-0002-2991-6333
Rinter KimathiCentre for Geographic Medicine Research (Coast), Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.
Stefan DiehlCentre of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0002-8058-7897
Fauzia K MusasiaCentre of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0003-1146-3003
Micha RosenkranzCentre of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0002-0337-4150
Patricia NjugunaCentre for Geographic Medicine Research (Coast), Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.ORCID 0000-0001-9585-3820
Mainga HamalubaCentre for Geographic Medicine Research (Coast), Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.ORCID 0000-0002-0266-1414
Melissa C KapuluCentre for Geographic Medicine Research (Coast), Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.ORCID 0000-0003-0321-7128
Roland FrankCentre of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany.
CHMI-SIKA Study Team
Faith H A OsierCentre of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0001-7133-5375
Abdirahman I Abdi
Primus Che Chi
Zaydah de Laurent
Irene Jao
Dorcas Kamuya
Gathoni Kamuyu
Johnstone Makale
Linda Murungi
Jennifer Musyoki
Michelle Muthui
Jedidah Mwacharo
Silvia Kariuki
Daniel Mwanga
Joyce Mwongeli
Francis Ndungu
Maureen Njue
George Nyangweso
Domitila Kimani
Joyce M Ngoi
Janet Musembi
Omar Ngoto
Edward Otieno
Michael Ooko
Jimmy Shangala
Juliana Wambua
Khadija Said Mohammed
Donwilliams Omuoyo
Moses Mosobo
Nelson Kibinge
Sam Kinyanjui
Philip Bejon
Brett Lowe
Kevin Marsh
Vicki Marsh
Yonas Abebe
Peter F Billingsley
Betty Kim Lee Sim
Stephen L Hoffman
Eric R James
Thomas L Richie
Agnes Audi
Fredrick Olewe
James Oloo
John Ongecha
Martin O Ongas
Nelly Koskei
Peter C Bull
Susanne H Hodgson
Cheryl Kivisi
Mallika Imwong
Sean C Murphy
Bernhards Ogutu
Joel Tarning
Markus Winterberg
Thomas N Williams
Heidelberg University · DEKenya Medical Research Institute · KEUniversity of the Witwatersrand · ZA
Funding
Department of Health 16/136/33Wellcome Trust 107499
Abstract
Natural killer (NK) cells are potent immune effectors that can be activated via antibody-mediated Fc receptor engagement. Using multiparameter flow cytometry, we found that NK cells degranulate and release IFN-γ upon stimulation with antibody-opsonized
Indexed as
MalariaMalaria, FalciparumAdultAnimalsAntibodies, ProtozoanAntigens, ProtozoanChildCohort StudiesHumansKiller Cells, NaturalMerozoitesPlasmodium falciparumAntibodies, ProtozoanAntigens, Protozoan
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.