ArticleSports medicine - open2023
Influence of Resistance Training Proximity-to-Failure, Determined by Repetitions-in-Reserve, on Neuromuscular Fatigue in Resistance-Trained Males and Females.
Article in Sports medicine - open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- The Effects of Advanced Resistance Training Prescription Methods on Strength, Power, Hypertrophy, and Performance Adaptations in Healthy Adults: A Systematic Review and Bayesian Network Meta-analysis.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Effects of resistance training performed to repetition non-failure on exercise performance in healthy adults: a systematic review and meta-analysis.BMC sports science, medicine & rehabilitation · 2026Pooled it
- Effects of Intensity and Fatigue on the Kinetics and Kinematics of the Barbell Squat, Bench Press, and Deadlift in Experienced Lifters: A Systematic Review.Sports medicine - open · 2025Pooled it
- Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions.Sports medicine (Auckland, N.Z.) · 2024Pooled it
- The Effect of Proximity-To-Failure on Perceptual Responses to Resistance Training.European journal of sport science · 2025Trial
- Perceived Exertion, Neuromuscular Activation, and Training Volume in Older Adults: Validating RPE-1 in Moderate-Velocity Elastic Band Resistance Training.International journal of sports physical therapy · 2026Article
- Blood Flow Restriction Training Prior to and After Anterior Cruciate Ligament Reconstruction: A Scoping Review.Journal of functional morphology and kinesiology · 2025Review
- Effects of a 5-Day Back Squat Overreaching Protocol on Strength Performance, Perceived Recovery and Wellness Responses: A Pilot Trial.Journal of functional morphology and kinesiology · 2025Article
- Oxygen consumption efficiency in firefighters: roles of fatigue and rescue task.Frontiers in physiology · 2025Article
- The Effect of Effort During a Resistance Exercise Session on Glycemic Control in Individuals Living With Prediabetes or Type 2 Diabetes: Protocol for a Crossover Randomized Controlled Trial.JMIR research protocols · 2024Article
- Sex differences in fatiguability during single-joint resistance exercise in a resistance-trained population.European journal of applied physiology · 2024Article
- Feasibility and Usefulness of Repetitions-In-Reserve Scales for Selecting Exercise Intensity: A Scoping Review.Perceptual and motor skills · 2024Article
- Cardiovascular, perceptual, and performance responses to single- vs. multi-chambered blood flow restriction cuffs.Frontiers in sports and active living · 2024Article
- Unpacking the blood flow restriction device features literature: multi-chambered bladder design.Frontiers in sports and active living · 2024Article
- Article
- Effect of Blood Flow Restriction during the Rest Periods of Squats on Accuracy of Estimated Repetitions to Failure.Sports (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study examined the influence of proximity-to-failure in resistance training (RT), using subjective repetitions-in-reserve (RIR) prediction, on neuromuscular fatigue and perceptual responses.
methodsTwenty-four resistance-trained males (n = 12) and females (n = 12) completed three experimental trials in a randomised order, each involving six RT sets (barbell bench press) with 75% 1-RM performed to either momentary muscular failure (FAIL), 1-RIR, or 3-RIR. Changes in lifting velocity with a fixed load were assessed from pre-exercise to post-exercise with the aim of quantifying acute neuromuscular fatigue (4 min post-exercise) and the associated time course of recovery (24 and 48 h post-exercise), and from the first to final set performed. Perceptual responses to RT were assessed at multiple time points during and following RT.
resultsDecreases in lifting velocity at 4 min post-exercise were greater for FAIL ( - 25%) versus 1-RIR ( - 13%) and 3-RIR ( - 8%), with greater decreases for male ( - 29%) versus female ( - 21%) participants following FAIL. At 24 h post-exercise, decreases in lifting velocity were greater for FAIL ( - 3%) and 1-RIR ( - 3%) versus 3-RIR (+ 2%), with all between-protocol differences diminishing at 48 h post-exercise. Loss of lifting velocity from the first to final set was greater for FAIL ( - 22%) versus 1-RIR ( - 9%) and 3-RIR ( - 6%), with a greater lifting velocity loss from the first to final set for males ( - 15%) versus females ( - 9%). As proximity-to-failure neared, ratings of perceived discomfort, exertion, and muscle soreness increased, general feelings worsened, and perceived recovery decreased.
conclusionThese findings support a linear relationship between RT proximity-to-failure and both acute neuromuscular fatigue and negative perceptual responses, which may influence long-term physiological adaptations and adherence to RT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.