Evidence map›Paper›PMID 36752722›Full record

ArticleEnvironmental microbiology2023

Interplay between transcriptional regulators and VapBC toxin-antitoxin loci during thermal stress response in extremely thermoacidophilic archaea.

Charlotte R Cooper, April M Lewis, Jaspreet S Notey, Arpan Mukherjee, Daniel J Willard, Paul H Blum, Robert M Kelly

Open access · greenAbstract read
In one paragraph

Article in Environmental microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Membrane lipid and expression responses ofFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Charlotte R CooperDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA.
April M LewisDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA.
Jaspreet S NoteyDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA.
Arpan MukherjeeDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA.
Daniel J WillardDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA.
Paul H BlumBeadle Center for Genetics, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Robert M KellyDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA.ORCID 0000-0002-0639-3592
North Carolina State University · USUniversity of Nebraska–Lincoln · US

Funding

Molecular Biotechnology Training at North Carolina State UniversityT32GM008776 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI KELLY, ROBERT M · 2000 to 2019
$3.9M
NC STATE MOLECULAR BIOTECHNOLOGY TRAINING PROGRAM (MBTP)T32GM133366 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Jason M. Haugh, Robert M Kelly · 2020 to 2026
$3.3M
Metabolic Engineering Studies of Extreme ThermoacidophilyR01GM090209 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI KELLY, ROBERT M · 2009 to 2010
$530k
NIGMS NIH HHS R01 GM090209NIGMS NIH HHS T32 GM008776NIGMS NIH HHS T32 GM133366
6 · The paper itself

Abstract

Thermoacidophilic archaea lack sigma factors and the large inventory of heat shock proteins (HSPs) widespread in bacterial genomes, suggesting other strategies for handling thermal stress are involved. Heat shock transcriptomes for the thermoacidophilic archaeon Saccharolobus (f. Sulfolobus) solfataricus 98/2 revealed genes that were highly responsive to thermal stress, including transcriptional regulators YtrA

Indexed as

AntitoxinsSulfolobus solfataricusToxins, BiologicalEscherichia coliHeat-Shock ResponseAntitoxinsToxins, Biological

Identifiers

PMID36752722
PMCPMC10580297
OpenAlexW4319461298

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.