Evidence map›Paper›PMID 36752390›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Small Molecule-Templated DNA Hydrogel with Record Stiffness Integrates and Releases DNA Nanostructures and Gene Silencing Nucleic Acids.

Christophe Lachance-Brais, Mostafa Rammal, Jathavan Asohan, Adam Katolik, Xin Luo, Daniel Saliba, Antranik Jonderian, Masad J Damha, Matthew J Harrington, Hanadi F Sleiman

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Design and Characterization of DX-Tile DNA Nanostar-Based Hydrogels.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  7. Supramolecular Interactions Modulate RNA:DNA Folding Observed via Nanopore Sensing.Angewandte Chemie (International ed. in English) · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
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  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Christophe Lachance-BraisDepartment of Chemistry, McGill University, 801 Sherbrooke St W, Montreal, H3A 0B8, Canada.ORCID 0000-0001-9211-4555
Mostafa RammalDepartment of Chemistry, McGill University, 801 Sherbrooke St W, Montreal, H3A 0B8, Canada.
Jathavan AsohanDepartment of Chemistry, McGill University, 801 Sherbrooke St W, Montreal, H3A 0B8, Canada.ORCID 0000-0002-0108-8361
Adam KatolikDepartment of Chemistry, McGill University, 801 Sherbrooke St W, Montreal, H3A 0B8, Canada.
Xin LuoDepartment of Chemistry, McGill University, 801 Sherbrooke St W, Montreal, H3A 0B8, Canada.ORCID 0000-0001-8116-5058
Daniel SalibaDepartment of Chemistry, McGill University, 801 Sherbrooke St W, Montreal, H3A 0B8, Canada.
Antranik JonderianDepartment of Chemistry, McGill University, 801 Sherbrooke St W, Montreal, H3A 0B8, Canada.ORCID 0000-0003-4357-2458
Masad J DamhaDepartment of Chemistry, McGill University, 801 Sherbrooke St W, Montreal, H3A 0B8, Canada.ORCID 0000-0002-4458-1623
Matthew J HarringtonDepartment of Chemistry, McGill University, 801 Sherbrooke St W, Montreal, H3A 0B8, Canada.
Hanadi F SleimanDepartment of Chemistry, McGill University, 801 Sherbrooke St W, Montreal, H3A 0B8, Canada.ORCID 0000-0002-5100-0532
McGill University · CA

Funding

Canada Council for the ArtsCanada Research Chairs 950-231953Canada Research Chair Tier 2 Award 950-231953Fonds de Recherche du Québec - Nature et TechnologieNatural Sciences and Engineering Research Council of Canada 2018-05243NSERC Discovery RGPIN-2018-05243NSERC Vanier Scholarship
6 · The paper itself

Abstract

Deoxyribonucleic acid (DNA) hydrogels are a unique class of programmable, biocompatible materials able to respond to complex stimuli, making them valuable in drug delivery, analyte detection, cell growth, and shape-memory materials. However, unmodified DNA hydrogels in the literature are very soft, rarely reaching a storage modulus of 10

Indexed as

NanostructuresNucleic AcidsDNAGene SilencingHydrogelsDNAHydrogelsNucleic Acidsantisense oligonucleotidescyanuric acidDNADNA nanotechnologygene silencinghydrogelsstimuli responsivesupramolecular

Identifiers

PMID36752390
PMCPMC10131789
OpenAlexW4319460459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.