Evidence map›Paper›PMID 36752270›Full record

ArticleJournal of the American Heart Association2023

Host-Microbiota Communication in Spontaneously Hypertensive Rats Generates Unique IgA-Coated Gut Microbes.

Jing Li, Elaine M Richards, Ramakumar Tummala, Carl J Pepine, Mohan K Raizada, Tao Yang

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jing LiKey Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Wuhan Botanical Garden Chinese Academy of Sciences Wuhan Hubei China.
Elaine M RichardsDepartment of Physiology and Functional Genomics University of Florida College of Medicine Gainesville FL USA.ORCID 0000-0002-1357-7410
Ramakumar TummalaDepartment of Physiology and Pharmacology Center for Hypertension and Precision Medicine College of Medicine and Life Sciences University of Toledo OH USA.ORCID 0000-0002-3887-3566
Carl J PepineDivision of Cardiovascular Medicine Department of Medicine University of Florida College of Medicine Gainesville FL USA.ORCID 0000-0002-6011-681X
Mohan K RaizadaDepartment of Physiology and Functional Genomics University of Florida College of Medicine Gainesville FL USA.ORCID 0000-0002-1654-9597
Tao YangDepartment of Physiology and Pharmacology Center for Hypertension and Precision Medicine College of Medicine and Life Sciences University of Toledo OH USA.ORCID 0000-0002-4182-9793
University of Florida · USUniversity of Toledo · US

Funding

Brain Angiotensin In Hypertensive Neurons in CultureR37HL033610 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K. · 2003 to 2012
$5.8M
BRAIN ANGIOTENSIN IN HYPERTENSIVE NEURONS IN CULTURER01HL033610 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K., SUMNERS, COLIN · 1985 to 2017
$4.3M
NHLBI NIH HHS R01 HL033610NHLBI NIH HHS R37 HL033610
6 · The paper itself

Abstract

Background Hypertension is associated with gut dysbiosis, altered intestinal immunity, and gut pathology in animal models and humans. Although these findings have implicated impaired interactions between gut and gut microbiota in hypertension, little is known about the specific functional gut microbes that interact with intestinal mucosa. Methods and Results To identify these microbes, we sorted Immunoglobin A (IgA)-coated (IgA

Indexed as

Gastrointestinal MicrobiomeHypertensionMicrobiotaAnimalsBacteriaHumansImmunoglobulin ARatsRats, Inbred SHRRats, Inbred WKYImmunoglobulin Ahost‐microbiota communicationhypertensionImmunoglobin A‐coated bacteria

Identifiers

PMID36752270
PMCPMC10111478
OpenAlexW4319461005

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.