Evidence map›Paper›PMID 36752115›Full record

ReviewIntegrative cancer therapies

The Role of Ketogenic Diet in the Treatment of Neuroblastoma.

Rangarirai Makuku, Zeinab Sinaei Far, Neda Khalili, Alistar Moyo, Sepideh Razi, Mahsa Keshavarz-Fathi, Maryam Mahmoudi, Nima Rezaei

Open access · goldAbstract readReview
In one paragraph

Review in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Construction of a disulfidptosis-related glycolysis gene risk model to predict the prognosis and immune infiltration analysis of gastric adenocarcinoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Rangarirai MakukuTehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-3305-2053
Zeinab Sinaei FarTehran University of Medical Sciences, Tehran, Iran.
Neda KhaliliTehran University of Medical Sciences, Tehran, Iran.
Alistar MoyoUniversal Scientific Education and Research Network (USERN), Harare, Zimbabwe.
Sepideh RaziTehran University of Medical Sciences, Tehran, Iran.
Mahsa Keshavarz-FathiTehran University of Medical Sciences, Tehran, Iran.
Maryam MahmoudiTehran University of Medical Sciences, Tehran, Iran.
Nima RezaeiTehran University of Medical Sciences, Tehran, Iran.
Universal Scientific Education and Research Network · IRTehran University of Medical Sciences · IRZimbabwe AIDS Network · ZW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ketogenic diet (KD) was initially used in 1920 for drug-resistant epileptic patients. From this point onward, ketogenic diets became a pivotal part of nutritional therapy research. To date, KD has shown therapeutic potential in many pathologies such as Alzheimer's disease, Parkinson's disease, autism, brain cancers, and multiple sclerosis. Although KD is now an adjuvant therapy for certain diseases, its effectiveness as an antitumor nutritional therapy is still an ongoing debate, especially in Neuroblastoma. Neuroblastoma is the most common extra-cranial solid tumor in children and is metastatic at initial presentation in more than half of the cases. Although Neuroblastoma can be managed by surgery, chemotherapy, immunotherapy, and radiotherapy, its 5-year survival rate in children remains below 40%. Earlier studies have proposed the ketogenic diet as a possible adjuvant therapy for patients undergoing treatment for Neuroblastoma. In this study, we seek to review the possible roles of KD in the treatment of Neuroblastoma.

Indexed as

Diet, KetogenicNeuroblastomaChildCombined Modality TherapyHumansTreatment Outcomeadjuvant therapychildhood malignanciesketogenic dietNeuroblastomanutritional therapyWarburg Effect

Identifiers

PMID36752115
PMCPMC9909060
OpenAlexW4319461837

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.