Evidence map›Paper›PMID 36752095›Full record

ArticleHypertension (Dallas, Tex. : 1979)2023

Significant Improvement in Blood Pressure Levels Among Older Adults With Hypertension in Rural South Africa.

Enrico G Ferro, Shafika Abrahams-Gessel, David Kapaon, Brian Houle, Jacques Du Toit, Ryan G Wagner, F Xavier Gómez-Olivé, Alisha N Wade, Chodziwadziwa W Kabudula, Stephen Tollman and 1 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Enrico G FerroDivision of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA (E.G.F.).
Shafika Abrahams-GesselCenter for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, MA (S.A.-G., D.K., F.X.G.-O., A.N.W., S.T., T.A.G.).ORCID 0000-0003-4954-057X
David KapaonCenter for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, MA (S.A.-G., D.K., F.X.G.-O., A.N.W., S.T., T.A.G.).
Brian HouleSchool of Demography, The Australian National University, Canberra (B.H.).ORCID 0000-0003-2157-3118
Jacques Du ToitFaculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (B.H., J.D.T., R.G.W., F.X.G.-O., A.N.W., C.W.K., S.T., T.A.G.).ORCID 0000-0002-0003-0168
Ryan G WagnerFaculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (B.H., J.D.T., R.G.W., F.X.G.-O., A.N.W., C.W.K., S.T., T.A.G.).ORCID 0000-0003-2741-3676
F Xavier Gómez-OlivéCenter for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, MA (S.A.-G., D.K., F.X.G.-O., A.N.W., S.T., T.A.G.).ORCID 0000-0002-4876-0848
Alisha N WadeCenter for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, MA (S.A.-G., D.K., F.X.G.-O., A.N.W., S.T., T.A.G.).ORCID 0000-0002-1158-2523
Chodziwadziwa W KabudulaFaculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (B.H., J.D.T., R.G.W., F.X.G.-O., A.N.W., C.W.K., S.T., T.A.G.).ORCID 0000-0002-5867-0336
Stephen TollmanCenter for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, MA (S.A.-G., D.K., F.X.G.-O., A.N.W., S.T., T.A.G.).ORCID 0000-0003-0744-7588
Thomas A GazianoCenter for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, MA (S.A.-G., D.K., F.X.G.-O., A.N.W., S.T., T.A.G.).ORCID 0000-0002-5985-345X
Harvard University · USUniversity of London · GBUniversity of the Witwatersrand · ZAAustralian National University · AUBeth Israel Deaconess Medical Center · US

Funding

SOCIAL AND ECONOMIC PREDICTORS OF PHYSICAL AND COGNITIVE FUNCTIONP01AG041710 · NIA · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Michele Michele Ramsay · 2013 to 2026
$37.3M
Endocrine and metabolic diseases in rural South Africa-establishing burden and improving detectionK43TW010698 · FIC · WITS HEALTH CONSORTIUM (PTY), LTD · PI WADE, ALISHA NICOLE · 2017 to 2021
$581k
FIC NIH HHS K43 TW010698NIA NIH HHS P01 AG041710
6 · The paper itself

Abstract

backgroundSub-Saharan Africa is undergoing an epidemiologic transition from infectious diseases to cardiovascular diseases. From 2014 to 2019, sociodemographic surveillance was performed in a large cohort in rural South Africa.

methodsDisease prevalence and incidence were calculated using inverse probability weights. Poisson regression was used to identify disease predictors. The percentage of individuals with controlled (<140/90 mm Hg) versus uncontrolled hypertension was compared between 2014 and 2019.

resultsCompared with 2014 (n=5059), study participants in 2019 (n=4176) had similar rates of obesity (mean body mass index, 27.5±10.0 versus 27.0±6.5) but higher smoking (9.1% versus 11.5%) and diabetes (11.1% versus 13.9%). There was no significant increase in hypertension prevalence (58.4% versus 59.8%; age adjusted, 64.3% versus 63.3%), and there was a significant reduction in mean systolic blood pressure (138.0 versus 128.5 mm Hg;

conclusionsThe hypertension prevalence and incidence are plateauing in this aging cohort. There was a statistically and clinically significant decline in mean blood pressure and a substantial increase in individuals with controlled hypertension on medication. The prevalence of cardiometabolic risk factors did not decrease over time, suggesting that the blood pressure decrease is likely due to increased medication access and adherence, promoted by local health systems.

Indexed as

Cardiovascular DiseasesHypertensionAgedBlood PressureHumansPrevalenceRisk FactorsSouth AfricaAfrica south of the Saharadeveloping countrieshealth services accessibilityhypertensionmedication adherence

Identifiers

PMID36752095
PMCPMC10363191
OpenAlexW4319461259

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.