Evidence map›Paper›PMID 36751781›Full record

ReviewNeural regeneration research2023

Role of vascular endothelial growth factor as a critical neurotrophic factor for the survival and physiology of motoneurons.

Paula M Calvo, Rosendo G Hernández, Rosa R de la Cruz, Angel M Pastor

Open access · goldAbstract readReview
In one paragraph

Review in Neural regeneration research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Peripheral nerve repair: innovations and future directions.Journal of translational medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Paula M CalvoDepartamento de Fisiología, Facultad de Biología, Universidad de Sevilla, Sevilla, Spain.
Rosendo G HernándezDepartamento de Fisiología, Facultad de Biología, Universidad de Sevilla, Sevilla, Spain.
Rosa R de la CruzDepartamento de Fisiología, Facultad de Biología, Universidad de Sevilla, Sevilla, Spain.
Angel M PastorDepartamento de Fisiología, Facultad de Biología, Universidad de Sevilla, Sevilla, Spain.
Universidad de Sevilla · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular endothelial growth factor (VEGF) was discovered by its angiogenic activity. However, during evolution, it appeared earlier as a neurotrophic factor required for the development of the nervous system in invertebrates lacking a circulatory system. We aimed at reviewing recent evidence indicating that VEGF has neuroprotective effects in neurons exposed to a variety of insults. Of particular interest is the link established between VEGF and motoneurons, especially after the design of the VEGF

Indexed as

abducens nucleusamyotrophic lateral sclerosiscell deathextracellular single-unit recordingseye movementsneurodegenerationoculomotortrophic factors

Identifiers

PMID36751781
PMCPMC10154470
OpenAlexW4312688775

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.