Evidence map›Paper›PMID 36751677›Full record

ArticleThe East African health research journal2022

Correlation of Malaria Rapid Test and Peripheral Blood Smear Microscopy among Patients attending Byumba Health Centre.

Cedrick Izere, Joyce Niyigena, Jean de Dieu Tuyishime, Alexis Nshimiyimana, Thierry Habyarimana, Pacifique Ndishimye, Callixte Yadufashije, Francois N Niyonzima

Open access · diamondAbstract read
In one paragraph

Article in The East African health research journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Cedrick IzereDepartment of Biomedical Laboratory Sciences, Ines-Ruhengeri Institute of Applied Sciences, Musanze district, Northern Province, Rwanda.
Joyce NiyigenaDepartment of Biomedical Laboratory Sciences, Ines-Ruhengeri Institute of Applied Sciences, Musanze district, Northern Province, Rwanda.
Jean de Dieu TuyishimeDepartment of Biomedical Laboratory Sciences, Ines-Ruhengeri Institute of Applied Sciences, Musanze district, Northern Province, Rwanda.
Alexis NshimiyimanaDepartment of Biomedical Laboratory Sciences, Ines-Ruhengeri Institute of Applied Sciences, Musanze district, Northern Province, Rwanda.
Thierry HabyarimanaDepartment of Biomedical Laboratory Sciences, Ines-Ruhengeri Institute of Applied Sciences, Musanze district, Northern Province, Rwanda.
Pacifique NdishimyeDepartment of Medical Research Center, Rwanda Biomedical Center, Kigali City, Rwanda.
Callixte YadufashijeDepartment of Public Health, Kampala University, Kampala, Uganda.
Francois N NiyonzimaDepartment of Math, Science and PE, CE, University of Rwanda, Rwamagana-55, Rwanda.
INES-Ruhengeri · RWKampala University · UGRwanda Biomedical Center · RWUniversity of Rwanda · RW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Malaria presents a diagnostic challenge in most tropical countries including Rwanda. Microscopy remains the gold standard for diagnosing malaria, however, it is labour intensive and depends upon the skill of the examiner. Malaria rapid diagnostic tests (MRDTs) have been developed as an easy, convenient alternative to microscopy. Methods: A cross sectional study was conducted from October to November 2019 on 130 febrile patients who were directed to the laboratory department for blood screening for malaria parasites at Byumba Health centre. The main objective of this study was to correlate Microscopy and MRDTs in diagnosis of malaria. Results: After signing a consent form, blood samples were collected and screened for malaria parasites microscopically and by using MRDTs. Data collection forms were filled with relevant information and obtained results for MRDTs and for peripheral blood smear were recorded. The collected data were statistically analyzed using GraphPad Prism 9 software. The mean age found to be 16 years old. In this study peripheral blood smear microscopy was considered as a reference method. The sensitivity and specificity of RDT Histidine-Rich Protein 2 (HRP-2) were calculated and found to be 96.6% and 60% respectively. The negative predictive value was found to be 92.85% where positive predictive value was 73.3%. Conclusion: MRDTs should be used along with microscopy to avert complications associated with delayed diagnosis and similar studies are required to identify alternative techniques with high specificity for the diagnosis of malaria.

Identifiers

PMID36751677
PMCPMC9887511
OpenAlexW4313345985

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.