Evidence map›Paper›PMID 36751660›Full record

ArticleJournal of immunotherapy and precision oncology2023

Images in Immunotherapy and Precision Oncology: Angiosarcoma of the Spleen and Liver.

Anagha Deshpande, Javier Munoz, Katalin Kelemen, Vrushali Dabak, Amr Hanbali, Razelle Kurzrock

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of immunotherapy and precision oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Application value ofFrontiers in oncology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 2 countries.

Anagha DeshpandeMayo Clinic Alix School of Medicine, Scottsdale, AZ, USA.
Javier MunozDepartment of Hematology, Mayo Clinic Arizona, Phoenix, AZ, USA.
Katalin KelemenDivision of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic Arizona, Phoenix, AZ, USA.
Vrushali DabakDepartment of Hematology and Oncology, Henry Ford Health System, Detroit, MI, USA.
Amr HanbaliKing Faisal Specialist Hospital, Riyadh, Saudi Arabia.
Razelle KurzrockMedical College of Wisconsin, Milwaukee, WI, USA.
Henry Ford Health System · USKing Faisal Specialist Hospital & Research Centre · SAMayo Clinic Hospital · USMayo Clinic in Arizona · USMayo Clinic in Florida · USWIN Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary splenic or hepatic angiosarcomas are ultra-rare and aggressive malignancies associated with poor prognosis. The mainstay treatments are surgical resection and chemotherapy. We report a case of angiosarcoma in a 50-year-old woman who presented with bruising, fatigue, ecchymosis, and hepatosplenomegaly. She was treated with the multi-kinase inhibitor sunitinib for 4 weeks before developing a splenic hemorrhage and succumbing. Recent studies have demonstrated the clinical benefit of immunotherapies in angiosarcomas. Additionally, sequencing techniques have showcased the diverse molecular aberrations involved in angiosarcomas, which offer opportunities for precision-matched targeted therapies such as inhibitors of the VEGF/VEGFR axis and PI3K/Akt/mTor pathway.

Indexed as

hepatic angiosarcomaipilimumabnivolumabsplenic angiosarcoma

Identifiers

PMID36751660
PMCPMC9888520
OpenAlexW4312213997

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.