Evidence map›Paper›PMID 36751502›Full record

ArticleBrain communications2022

Neuromuscular symptoms in patients with

Luuk R van den Bersselaar, Heinz Jungbluth, Nick Kruijt, Erik-Jan Kamsteeg, Miguel A Fernandez-Garcia, Susan Treves, Sheila Riazi, Ignacio Malagon, Lucas T van Eijk, Nens van Alfen and 4 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Exercise capacity in RYR1-related myopathies.Orphanet journal of rare diseases · 2025
    Trial
  2. Review
  3. Myopathies in clinical care: a focus on treatable causes.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Rycal S48168 (ARM210) forEClinicalMedicine · 2024
    Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 5 countries.

Luuk R van den BersselaarMalignant Hyperthermia Investigation Unit, Department of Anesthesiology, Canisius Wilhelmina Hospital, 6532 SZ Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0001-7735-3267
Heinz JungbluthDepartment of Paediatric Neurology, Neuromuscular Service, Evelina Children's Hospital, Guy's and St Thomas' Hospital NHS Foundation Trust, SE1 7EH London, UK.
Nick KruijtDepartment of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.
Erik-Jan KamsteegDepartment of Human Genetics, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.
Miguel A Fernandez-GarciaDepartment of Paediatric Neurology, Neuromuscular Service, Evelina Children's Hospital, Guy's and St Thomas' Hospital NHS Foundation Trust, SE1 7EH London, UK.
Susan TrevesDepartments of Biomedicine and Neurology, Neuromuscular research Group, University Hospital Basel, 4031 Basel, Switzerland.ORCID https://orcid.org/0000-0002-0007-9631
Sheila RiaziDepartment of Anesthesia, Malignant Hyperthermia Investigation Unit, University Health Network, University of Toronto, M5s 1a4 Toronto, Ontario, Canada.
Ignacio MalagonDepartment of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.
Lucas T van EijkDepartment of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.
Nens van AlfenDepartment of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.
Baziel G M van EngelenDepartment of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.
Gert-Jan SchefferDepartment of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.
Marc M J SnoeckMalignant Hyperthermia Investigation Unit, Department of Anesthesiology, Canisius Wilhelmina Hospital, 6532 SZ Nijmegen, The Netherlands.
Nicol C VoermansDepartment of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.
Radboud University Nijmegen · NLSt Thomas' Hospital · GBCanisius-Wilhelmina Ziekenhuis · NLUniversity Health Network · CAUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant hyperthermia and exertional rhabdomyolysis have conventionally been considered episodic phenotypes that occur in otherwise healthy individuals in response to an external trigger. However, recent studies have demonstrated a clinical and histopathological continuum between patients with a history of malignant hyperthermia susceptibility and/or exertional rhabdomyolysis and

Indexed as

exertional rhabdomyolysismalignant hyperthermiamyopathyryanodine receptor-1RYR1

Identifiers

PMID36751502
PMCPMC9897183
OpenAlexW4308884635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.