ArticleBrain communications2022
Focused ultrasound using a novel targeting method four-tract tractography for magnetic resonance-guided high-intensity focused ultrasound targeting.
Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Enhancing precision in MRgFUS for tremor treatment: a systematic review of tractography-based VIM targeting approaches.Neurosurgical review · 2025Pooled it
- State of Practice on Transcranial MR-Guided Focused Ultrasound: A Report from the ASNR Standards and Guidelines Committee and ACR Commission on Neuroradiology Workgroup.AJNR. American journal of neuroradiology · 2025Guideline
- The emerging role of high-intensity focused ultrasound (HIFU) as a symptomatic treatment for Parkinson's disease and essential tremor: a narrative review.Arquivos de neuro-psiquiatria · 2026Review
- Is It Safe to Have Deep Brain Stimulation after MRI-Guided Focused Ultrasound Ablation? A Report of Three Cases and Review of Literature.Stereotactic and functional neurosurgery · 2026Article
- Stroke Mimicking Thalamotomy in Primary Familial Brain Calcification.Movement disorders clinical practice · 2025Article
- MR-guided focused ultrasound thalamotomy in a patient with thrombocytopenia: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Magnetic resonance-guided focused ultrasound thalamotomy as a viable option for essential tremor after deep brain stimulation explantation: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Bilateral Focused Ultrasound Thalamotomy for Essential Tremor: Clinical Outcomes Compared to Bilateral Deep Brain Stimulation and Probabilistic Lesion Mapping.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- The scientific value of tractography: accuracy vs usefulness.Brain structure & function · 2025Article
- Bilateral Lesions in Parkinson's Disease: Gaps and Controversies.Movement disorders : official journal of the Movement Disorder Society · 2025Review
- Plasma glial fibrillary acidic protein as a biomarker of acute focal brain injury after high-intensity focused ultrasound thalamotomy.Brain communications · 2025Article
- Four-tract tractography: multiparametric direct targeting of the dentatorubrothalamic tract.Neurosurgical focus: Video · 2024Article
- Practical Targeting Errors During Optically Tracked Transcranial Focused Ultrasound Using MR-ARFI and Array- Based Steering.IEEE transactions on bio-medical engineering · 2024Article
- When millimeters matter.European radiology · 2024Article
- Four-tract probabilistic tractography technique for target selection in essential tremor treatment with magnetic resonance-guided focused ultrasound.European radiology · 2024Article
- Magnetic resonance imaging-guided focused ultrasound thalamotomy for essential tremor in a patient with von Willebrand disease: perioperative optimization for patients with coagulopathies. Illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- First High Intensity Focused Ultrasound Thalamotomy in a Patient with Cerebral Aneurysms.Movement disorders clinical practice · 2024Article
- "Quality over quantity:" smaller, targeted lesions optimize quality of life outcomes after MR-guided focused ultrasound thalamotomy for essential tremor.Frontiers in neurology · 2024Article
- One-pass deep brain stimulation of subthalamic nucleus and ventral intermediate nucleus for levodopa-resistant tremor-dominant Parkinson's disease.Frontiers in aging neuroscience · 2023Article
- Improving tremor response to focused ultrasound thalamotomy.Brain communications · 2023Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Magnetic resonance-guided high-intensity focused ultrasound thalamotomy is a Food and Drug Administration-approved treatment for essential tremor. The target, the ventral intermediate nucleus of the thalamus, is not visualized on standard, anatomic MRI sequences. Several recent reports have used diffusion tensor imaging to target the dentato-rubro-thalamic-tract. There is considerable variability in fibre tracking algorithms and what fibres are tracked. Targeting discrete white matter tracts with magnetic resonance-guided high-intensity focused ultrasound is an emerging precision medicine technique that has the promise to improve patient outcomes and reduce treatment times. We provide a technical overview and clinical benefits of our novel, easily implemented advanced tractography method: four-tract tractography. Our method is novel because it targets both the decussating and non-decussating dentato-rubro-thalamic-tracts while avoiding the medial lemniscus and corticospinal tracts. Our method utilizes Food and Drug Administration-approved software and is easily implementable into existing workflows. Initial experience using this approach suggests that it improves patient outcomes by reducing the incidence of adverse effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.