Evidence map›Paper›PMID 36751336›Full record

ArticleSkin health and disease2023

Radiation-induced morphea of the breast-A case series.

Paula Finnegan, Lisa Kiely, Catriona Gallagher, Sarah Ni Mhaolcatha, Linda Feeley, Jim Fitzgibbon, Jessica White, John Bourke, Lesley Ann Murphy

Open access · goldAbstract readCase Reports
In one paragraph

Article in Skin health and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Paula FinneganDepartment of Dermatology University Hospital Limerick Dooradoyle Limerick Ireland.ORCID https://orcid.org/0000-0002-2663-1359
Lisa KielyDepartment of Dermatology South Infirmary Victoria University Hospital Cork Ireland.ORCID https://orcid.org/0000-0003-1100-8692
Catriona GallagherDepartment of Dermatology South Infirmary Victoria University Hospital Cork Ireland.ORCID https://orcid.org/0000-0003-1437-7311
Sarah Ni MhaolcathaDepartment of Histopathology Cork University Hospital Wilton, Cork Ireland.
Linda FeeleyDepartment of Histopathology Cork University Hospital Wilton, Cork Ireland.
Jim FitzgibbonDepartment of Histopathology Cork University Hospital Wilton, Cork Ireland.
Jessica WhiteDepartment of Histopathology Cork University Hospital Wilton, Cork Ireland.
John BourkeDepartment of Dermatology South Infirmary Victoria University Hospital Cork Ireland.
Lesley Ann MurphyDepartment of Dermatology South Infirmary Victoria University Hospital Cork Ireland.
Cork University Hospital · IESouth Infirmary Victoria University Hospital · IEUniversity Hospital Limerick · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiation-induced morphea (RIM) is a rare but recognized late complication of radiotherapy. It was first described in 1905, not long after the initial discovery of X-rays by Roentgen. Characterized by the deposition of excess collagen in the dermis, it results in thickening of the skin. Its frequency is approximately 2 in 1000. We present a series of three cases involving patients receiving radiotherapy treatment for breast cancer, each of which subsequently developed RIM. Because of its rarity, RIM is often misdiagnosed as infection or metastatic disease. This can lead to delayed diagnosis and treatment, leading to poorer outcomes such as chronic pain issues. Early dermatological involvement and tissue sampling to examine histopathological features can avoid this, leading to better care and improved results. A variety of treatment options are available, ranging from topical to systemic, with early induction more likely to result in a positive response.

Identifiers

PMID36751336
PMCPMC9892419
OpenAlexW4283753331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.