ArticleCureus2023
Immunohistochemical Expression of BCL-2 in Endometrial Carcinoma and Its Comparison With Hormone Receptor Status and Epidermal Growth Factor.
Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
- ob/ob obese mice promote tumorigenesis of endometrial cancer associated with Pten deficiency.Endocrine-related cancer · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndometrial carcinoma is the most common malignant tumor of the female genital tract with increasing incidence in developed countries. In the era of targeted therapy, immunohistochemical markers play an important role in the treatment and prognosis of endometrial carcinoma. The aim of the study was to study the immunohistochemical expression of B-cell lymphoma 2 (BCL-2) in endometrial carcinoma and to study the correlation of BCL-2 expression with hormone receptor status and transforming growth factor receptors in endometrial carcinoma.
methodsEndometrial carcinoma reported between the period from January 2010 to December 2014 in the department of pathology of this institute was considered in the study. The study included cases of endometrial carcinoma reported on both curetting and hysterectomy specimens. In the samples where both curetting and hysterectomy were received only hysterectomy blocks were included and the curetting was excluded.
resultsThe total number of malignancies reported during this period was 3478. Of these 3478 malignancies, 59 were endometrial carcinomas with an incidence of 1.6%. Out of 59 endometrial carcinomas, 46 cases were diagnosed on hysterectomy specimens and 13 cases were diagnosed on endometrial curetting biopsies.
conclusionThe positive expressions of estrogen receptor (ER) and progesterone receptor (PR) in endometrial carcinoma suggest that steroid receptor studies may be of potential benefit in the management of some patients with endometrial carcinoma.
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Registered trials
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