Evidence map›Paper›PMID 36751006›Full record

ArticlePediatric transplantation2023

Temporal trends in primary payers in pediatric heart transplant and association with long-term survival.

Kathryn Restaino, Xuemei Zhang, Jennifer A Faerber, Joseph W Rossano, Danielle Burstein, Carol A Wittlieb-Weber, Kimberly Yee Lin, Jonathan B Edelson, Jonathan J Edwards, Matthew J O'Connor

Open access · greenAbstract read
In one paragraph

Article in Pediatric transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kathryn RestainoDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-4456-8111
Xuemei ZhangData Science and Biostatistics Team, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Jennifer A FaerberData Science and Biostatistics Team, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Joseph W RossanoDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Danielle BursteinDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Carol A Wittlieb-WeberDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Kimberly Yee LinDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-1582-9797
Jonathan B EdelsonDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Jonathan J EdwardsDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Matthew J O'ConnorDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Children's Hospital of Philadelphia · US

Funding

Defining the Role of ROR2 in Right Ventricular Failure PathogenesisK08HL159311 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI EDWARDS, JONATHAN JOSEPH · 2021 to 2025
$657k
NHLBI NIH HHS K08 HL159311
6 · The paper itself

Abstract

backgroundPediatric heart transplantation (HT) is resource intensive. In adults, there has been an increase in the proportion of HTs funded by public insurance, with post-HT outcomes inferior to those funded by private sources. Trends in the funding of pediatric HT and outcomes in children have not been described.

methodsWe queried the United Network for Organ Sharing (UNOS) database for children (<18 years) listed for and undergoing HT between 2004 and 2021. We identified the primary payer at listing, HT, 1 year, and 1-5 years following HT. Trends were analyzed using generalized logit models. Multivariable-extended Cox regression models were used to test the relationship between insurance type at the time of transplant and time to death or re-transplant.

resultsThere were 6382 pediatric patients who underwent transplants and had either public or private insurance at the time of transplant. The percentage of patients with public insurance at the time of HT increased over time. Public insurance at the time of HT was associated with an increased risk of death or re-transplant beyond 2 months after HT (adjusted HR at 6 months = 1.43, 95% CI: 1.13-1.81, p = .003; adjusted HR at 9 months = 1.67, 95% CI: 1.17-2.37, p = .004).

conclusionThere has been a statistically significant trend toward increasing public insurance for children awaiting, at the time of, and after HT. Black patients and those with public insurance at HT have worse long-term outcomes. This study highlights ongoing disparities in pediatric HT and the need to focus efforts on achieving equitable outcomes.

Indexed as

Heart TransplantationAdultChildDatabases, FactualHumansProportional Hazards ModelsRetrospective StudiesRisk FactorsTime Factorsdisparitiesheart transplantationinsuranceoutcomespediatric

Identifiers

PMID36751006
PMCPMC10290494
OpenAlexW4319460905

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.