Evidence map›Paper›PMID 36750981›Full record

ArticleJournal of the International Neuropsychological Society : JINS2023

Longitudinal association between executive function and academic achievement in children with neurofibromatosis type 1 and plexiform neurofibromas.

Yang Hou, Xian Wu, Taryn Allen, Mary Anne Toledo-Tamula, Staci Martin, Andy Gillespie, Anne Goodwin, Brigitte C Widemann, Pamela L Wolters

Open access · hybridAbstract read
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yang HouDepartment of Behavioral Sciences and Social Medicine, Florida State University, Tallahassee, FL, USA.ORCID 0000-0002-7360-5751
Xian WuDepartment of Behavioral Sciences and Social Medicine, Florida State University, Tallahassee, FL, USA.
Taryn AllenPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Mary Anne Toledo-TamulaClinical Research Directorate (CRD), Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Staci MartinPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Andy GillespiePediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Anne GoodwinPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Brigitte C WidemannPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Pamela L WoltersPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
National Cancer Institute · USFlorida State University · USFrederick National Laboratory for Cancer Research · US

Funding

WORK ORDER 126643 B539 EXPAND IC SUITE75N91019D00024 · NIAID · LEIDOS BIOMEDICAL RESEARCH, INC. · PI PENDLETON, RICHARD · 2019 to 2025
$3932.6M
Therapies for patients with rare tumors and genetic tumor predispositionZIASC010354 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI WIDEMANN, BRIGITTE · 2009 to 2025
$19.2M
Pediatric Oncology Branch Behvioral Science CoreZIDBC011517 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI GLOD, JOHN · 2013 to 2025
$15.6M
Intramural NIH HHS ZIA SC010354Intramural NIH HHS ZID BC011517NCI NIH HHS 75N91019D00024
6 · The paper itself

Abstract

objectiveTo examine how executive functioning (EF) relates to academic achievement longitudinally in children with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PNs) and whether age at baseline moderates this relationship.

methodParticipants included 88 children with NF1 and PNs (ages 6-18 years old,

resultsThe relationship between EF and academic achievement varied across EF and academic domains. Cognitive flexibility (PB) uniquely explained more variances in initial math, reading, and writing scores; working memory (PB) uniquely explained more variances in initial levels of reading and writing. The associations between EF and academic achievement tended to remain consistent across age groups with one exception: Lower initial levels of inhibitory control (PR) were related to a greater decline in reading scores. This pattern was more evident among younger (versus older) children.

conclusionsFindings emphasize the heterogeneous nature of academic development in NF1 and that EF skills could help explain the within-group variability in this population. Routine cognitive/academic monitoring via comprehensive assessments and early targeted treatments consisting of medication and/or systematic cognitive interventions are important to evaluate for improving academic performance in children with NF1 and PNs.

Indexed as

Academic SuccessNeurofibroma, PlexiformNeurofibromatosis 1AdolescentChildExecutive FunctionHumansLongitudinal StudiesMaleReadingattentioncognitioninhibitory controlmathmultilevel analysisneuropsychological testreadingworking memory

Identifiers

PMID36750981
PMCPMC10695331
OpenAlexW4319461532

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.