Evidence map›Paper›PMID 36750784›Full record

ArticleBMC geriatrics2023

A novel easy-to-use index to predict institutionalization and death in older population - a 10-year population-based follow-up study.

Elisa Heikkilä, Marika Salminen, Anna Viljanen, Taina Katajamäki, Marja-Kaisa Koivula, Kari Pulkki, Raimo Isoaho, Sirkka-Liisa Kivelä, Matti Viitanen, Minna Löppönen and 5 more

Abstract read
In one paragraph

Article in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Elisa HeikkiläFaculty of Medicine, Department of Clinical Medicine, Unit of Clinical Chemistry, Turku University, FI-20014 University of Turku, 20521, Turku, Finland. etmhei@utu.fi.ORCID 0000-0002-6768-6890
Marika SalminenFaculty of Medicine, Department of Clinical Medicine, Unit of Family Medicine, University of Turku and Turku University Hospital, 20014, Turku, Finland.
Anna ViljanenMunicipality of Lieto, Health Care Center, 21420, Lieto, Finland.
Taina KatajamäkiFaculty of Medicine, Department of Clinical Medicine, Unit of Clinical Chemistry, Turku University, FI-20014 University of Turku, 20521, Turku, Finland.
Marja-Kaisa KoivulaHUS Diagnostic Center, Helsinki University Hospital, Hospital District of Helsinki and Uusimaa (HUS), Helsinki, Finland.
Kari PulkkiHUS Diagnostic Center, Helsinki University Hospital, Hospital District of Helsinki and Uusimaa (HUS), Helsinki, Finland.
Raimo IsoahoFaculty of Medicine, Department of Clinical Medicine, Unit of Family Medicine, University of Turku and Turku University Hospital, 20014, Turku, Finland.
Sirkka-Liisa KiveläFaculty of Medicine, Department of Clinical Medicine, Unit of Family Medicine, University of Turku and Turku University Hospital, 20014, Turku, Finland.
Matti ViitanenFaculty of Medicine, Department of Geriatrics, Turku City Hospital, University of Turku, Kunnallissairaalantie 20, 20700, Turku, Finland.
Minna LöppönenCity of Raisio, Social and Health Care for Elderly, 21200, Raisio, Finland.
Tero VahlbergFaculty of Medicine, Department of Clinical Medicine, Unit of Biostatistics, University of Turku, Turku, Finland.
Mikko S VenäläinenTurku Bioscience Centre, University of Turku and Åbo Akademi University, 20520, Turku, Finland.
Laura L EloTurku Bioscience Centre, University of Turku and Åbo Akademi University, 20520, Turku, Finland.
Laura ViikariCity of Turku, Welfare Division/Turku City Hospital, Kunnallissairaalantie 20, 20700, Turku, Finland.
Kerttu IrjalaFaculty of Medicine, Department of Clinical Medicine, Unit of Clinical Chemistry, Turku University, FI-20014 University of Turku, 20521, Turku, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVarious indexes have been developed to estimate the risk for mortality, institutionalization, and other adverse outcomes for older people. Most indexes are based on a large number of clinical or laboratory parameters. An index based on only a few parameters would be more practical to use in every-day clinical practice. Our aim was to create an index to predict the risk for mortality and institutionalization with as few parameters as possible without compromising their predictive ability.

methodsA prospective study with a 10-year follow-up period. Thirty-six clinical and fourteen laboratory parameters were combined to form an index. Cox regression model was used to analyze the association of the index with institutionalization and mortality. A backward statistical method was used to reduce the number of parameters to form an easy-to-use index for predicting institutionalization and mortality.

resultsThe mean age of the participants (n = 1172) was 73.1 (SD 6.6, range 64‒97) years. Altogether, 149 (14%) subjects were institutionalized, and 413 (35%) subjects deceased during the follow-up. Institutionalization and mortality rates increased as index scores increased both for the large 50-parameter combined index and for the reduced indexes. After a backward variable selection in the Cox regression model, three clinical parameters remained in the index to predict institutionalization and six clinical and three laboratory parameters in the index to predict mortality. The reduced indexes showed a slightly better predictive value for both institutionalization and mortality compared to the full index.

conclusionsA large index with fifty parameters included many unimportant parameters that did not increase its predictive value, and therefore could be replaced with a reduced index with only a few carefully chosen parameters, that were individually associated with institutionalization or death.

Indexed as

InstitutionalizationAgedAged, 80 and overFollow-Up StudiesHumansProspective StudiesAgedIndexInstitutionalizationMortality

Identifiers

PMID36750784
PMCPMC9903495

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.