ArticleScientific reports2023
The effect of Computer Assisted Rehabilitation Environment (CAREN) in cognitive impairment and coping strategies in Parkinson's disease: a preliminary study.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of the computer-assisted rehabilitation environment on patient rehabilitation: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Instrumented gait characteristics and short-term changes after CAREN training in ischemic stroke: a pilot study.Frontiers in psychiatry · 2026Article
- Integrated bio-cooperative robotic platform for virtual cognitive training in Parkinson's disease: design and methodology of the OPERA project.Frontiers in neurology · 2025Article
- Implementation of the sensory organization test with the CAREN system: a pilot study.Frontiers in bioengineering and biotechnology · 2025Article
- Computer-assisted rehabilitation system in the use of motor function recovery: A protocol for scoping review.PloS one · 2025Article
- Do patients with neurological disorders benefit from immersive virtual reality? A scoping review on the emerging use of the computer-assisted rehabilitation environment.European journal of physical and rehabilitation medicine · 2024Article
- Improving Outcomes in People with Spinal Cord Injury: Encouraging Results from a Multidisciplinary Advanced Rehabilitation Pathway.Brain sciences · 2024Article
- Effectiveness and Feasibility of Nonpharmacological Interventions for People With Parkinson's Disease and Cognitive Impairment on Patient-Centred Outcomes: Systematic Review and Meta-Analysis.Parkinson's disease · 2024Article
- A feasibility and usability study of a virtual reality tool (VESPA 2.0) for cognitive rehabilitation in patients with mild cognitive impairment: an ecological approach.Frontiers in psychology · 2024Article
- Coupling neurologic music therapy with immersive virtual reality to improve executive functions in individuals with Parkinson's disease: A Quasi-Randomized Clinical Trial.Clinical parkinsonism & related disorders · 2024Article
- From real to virtual prism adaptation therapy: a systematic review on benefits and challenges of a new potential rehabilitation approach.Frontiers in psychology · 2024Review
- Might patients with cerebellar ataxia benefit from the Computer Assisted Rehabilitation ENvironment (CAREN)? A pilot study focusing on gait and balance.Frontiers in bioengineering and biotechnology · 2024Article
- Impact of CAVE automatic virtual environment (CAVE) on user experience and health outcomes: A systematic review.International journal of clinical and health psychology : IJCHPArticle
- Advancing rehabilitation in Parkinson's disease through virtual reality: a narrative review.Frontiers in neurologyReview
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parkinson's disease is a neurodegenerative disorder characterized by different motor, vegetative, behavioral, and cognitive impairments, with worsening quality of life. Virtual reality devices have given promising results in neurorehabilitation as they can provide multisensory stimulation in a realistic environment. This study aims to test the efficacy of virtual reality training by using Computer Assisted Rehabilitation Environment in cognitive impairment in a sample of PD. 31 patients affected by PD were enrolled. All PD patients underwent 24 sessions of Computer Assisted Rehabilitation Environment training. The participants were assessed at baseline (T0) and after two months (T1). Our results suggested that Computer Assisted Rehabilitation Environment training may be effective in the cognitive and emotional domains, particularly by improving executive function, anxiety, and depressive symptoms. These changes have helped to improve self-efficacy and coping strategies. These results indicate greater cognitive and physical effort to overcome stressors. Our results show that Computer Assisted Rehabilitation Environment training was beneficial in improving cognitive functions. Longer duration training may be especially beneficial for patients with mild cognitive impairment. Our findings open the door to tailored personalized treatments based on the patient's motor and cognitive profiles.
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