Evidence map›Paper›PMID 36750453›Full record

ArticleAnnals of dermatology2023

Which Areas Are Still Left in Biologics Responsive Korean Patients with Moderate to Severe Plaque Psoriasis.

Sang-Hyeon Won, Bong Seok Shin, Kyung-Nam Bae, Jin-Hwa Son, Kihyuk Shin, Hoon-Soo Kim, Hyun-Chang Ko, Moon-Bum Kim, Byung-Soo Kim

Abstract read
In one paragraph

Article in Annals of dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sang-Hyeon Won *Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0003-2785-5079
Bong Seok Shin *Department of Dermatology, Chosun University Hospital, Gwangju, Korea.ORCID https://orcid.org/0000-0001-9618-1763
Kyung-Nam BaeDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0003-3254-8401
Jin-Hwa SonDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0002-8720-7359
Kihyuk ShinDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0001-8955-9828
Hoon-Soo KimDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0002-7649-1446
Hyun-Chang KoDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0002-3459-5474
Moon-Bum KimDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0003-4837-0214
Byung-Soo KimDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0003-0054-8570

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPsoriasis localized to certain body areas, such as the scalp, nails, palms, soles, intertriginous regions, and genital regions, is reportedly difficult to treat.

objectiveTo investigate the biologics-resistant areas in South Korean patients with psoriasis treated with biologics.

methodsThe study included 50 patients with chronic moderate to severe plaque psoriasis from the Pusan National University Hospital and Chosun University Hospital between October 2019 and September 2020. The patients had at least one psoriatic lesion, were treated with biologics for more than six months, and exhibited a partial or good response (reaching a Psoriasis Area and Severity Index [PASI] score of 1~5 after biologics treatment).

resultsA total of 50 patients with psoriasis (32 male, mean±standard deviation 47.8±11 years), with a median PASI score of 1.8, were included. The most common biologics-resistant areas were the anterior lower leg (56.0%), followed by the knee (48.0%) and posterior lower leg (42.0%). The proportion of biologics-resistant areas were obtained for body regions traditionally considered as difficult-to-treat entities, including the fingernails (10.0%), toenails (14.0%), scalp (38.0%), palm (12.0%), sole (14.0%), and genital areas (10.0%).

conclusionThis study determined the biologics-resistant areas in South Korean patients, successfully treated with biologics, in a real-world clinical setting.

Indexed as

BiologicsKoreaPsoriasisQuality of life

Identifiers

PMID36750453
PMCPMC9905854

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.