Evidence map›Paper›PMID 36750276›Full record

ArticleBMJ open respiratory research2023

Association between tobacco product use and asthma among US adults from the Population Assessment of Tobacco and Health (PATH) Study waves 2-4.

Mary F Brunette, Michael J Halenar, Kathryn C Edwards, Kristie A Taylor, Jennifer A Emond, Susanne E Tanski, Steven Woloshin, Laura M Paulin, Andrew Hyland, Kristen Lauten and 7 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open respiratory research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  7. Impact of metabolic and weight components on incident asthma using a real-world cohort.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Article
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  13. Author Response to E-cigarettes and Respiratory Disorder: The Broader Research Context.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 1 country.

Mary F BrunetteResearch Division, Department of Psychiatry, Dartmouth Health, Lebanon, New Hampshire, USA Mary.F.Brunette@hitchcock.org.
Michael J HalenarBehavorial Health and Health Policy Practice, Westat, Rockville, Maryland, USA.
Kathryn C EdwardsBehavorial Health and Health Policy Practice, Westat, Rockville, Maryland, USA.
Kristie A TaylorBehavorial Health and Health Policy Practice, Westat, Rockville, Maryland, USA.
Jennifer A EmondDartmouth College Geisel School of Medicine, Hanover, New Hampshire, USA.
Susanne E TanskiDartmouth College Geisel School of Medicine, Hanover, New Hampshire, USA.
Steven WoloshinThe C Everette Koop Institute, Dartmouth College, Lebanon, New Hampshire, USA.
Laura M PaulinDartmouth College Geisel School of Medicine, Hanover, New Hampshire, USA.
Andrew HylandDepartment of Health and Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Kristen LautenBehavorial Health and Health Policy Practice, Westat, Rockville, Maryland, USA.
Martin MahoneyDepartment of Health and Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Carlos BlancoDivision of Epidemiology, Services and Prevention Research (DESPR), National Institute on Drug Abuse, Bethesda, Maryland, USA.
Nicolette BorekOffice of Science, Center for Tobacco Products, Silver Spring, Maryland, USA.
Louis Claudio DaSilvaOffice of Science, Center for Tobacco Products, Silver Spring, Maryland, USA.
Lisa D GardnerOffice of Science, Center for Tobacco Products, Silver Spring, Maryland, USA.
Heather L KimmelDivision of Epidemiology, Services and Prevention Research (DESPR), National Institute on Drug Abuse, Bethesda, Maryland, USA.
James D SargentDartmouth College Geisel School of Medicine, Hanover, New Hampshire, USA.
Dartmouth College · USWestat (United States) · USOffice of Science · USNational Institute on Drug Abuse · USRoswell Park Comprehensive Cancer Center · USDartmouth Psychiatric Research Center · US

Funding

NIDA NIH HHS HHSN271201100027CNIDA NIH HHS HHSN271201600001C
6 · The paper itself

Abstract

backgroundResearch on cigarettes and adult asthma offers mixed findings, perhaps due to overlap with chronic obstructive pulmonary disease (COPD) and inadequate adjustment for other smoke exposures. Associations between other tobacco products, including e-cigarettes, and asthma are also understudied. RESEARCH QUESTION: Using Population Assessment of Tobacco and Health Study waves 2-4 (2014/2015-2016/2017) data, we assessed the relation between tobacco product use and asthma in persons unlikely to have COPD. STUDY DESIGN AND

methodsProspective study of 10 267 adults aged 18-39 years without COPD diagnoses. Past-month tobacco use at wave 2 was modelled first as combustible versus non-combustible use and second as specific product categories (former, cigarettes, e-cigarettes, cigars, hookah, smokeless tobacco). Outcomes included lifetime asthma prevalence at wave 2, incidence (waves 3 and 4) and Asthma Control Test score (lower=worse). Multivariable regressions adjusted for predictors of asthma, including other smoke exposures: cigarette pack-years, secondhand smoke and marijuana use. Sensitivity analyses examined findings when persons >39 years and those with both COPD and asthma were added, and when smoke exposure adjustments were removed.

resultsNo product, including cigarettes and e-cigarettes, was associated with prevalence or incidence of asthma. Among people with asthma at wave 2, combustible tobacco (beta=-0.86, 95% CI (-1.32 to -0.39)) and cigarettes (beta=-1.14, 95% CI (-1.66 to -0.62)) were associated with worse asthma control. No tobacco product was associated with asthma control over time. In sensitivity analyses, tobacco use became associated with incident asthma as adults >39 years and those with asthma+COPD were added, and as adjustments for other smoke exposures were omitted.

interpretationAlthough cigarette use was associated with worse asthma control, there were no longitudinal associations between combustible tobacco or e-cigarette use and new onset or worsening asthma in these preliminary analyses. Research on tobacco and asthma should exclude COPD and adjust for smoking history and other smoke exposures.

Indexed as

AsthmaElectronic Nicotine Delivery SystemsPulmonary Disease, Chronic ObstructiveAdultHumansNicotianaPrevalenceProspective StudiesTobacco UseAsthmaTobacco and the lung

Identifiers

PMID36750276
PMCPMC9906250
OpenAlexW4319344986

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.