ArticleAging2023
Intrinsic capacity differs from functional ability in predicting 10-year mortality and biological features in healthy aging: results from the I-Lan longitudinal aging study.
Article in Aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Effectiveness of a multidomain lifestyle counseling intervention on intrinsic capacity in older women: a randomized clinical trial.Aging clinical and experimental research · 2025Trial
- Criterion validity of brief, comprehensive, and latent measures of intrinsic capacity against frailty, disability, and mortality in older adults.The journal of nutrition, health & aging · 2026Article
- Association between sedentary time and intrinsic capacity among community-dwelling older adults: evidence from a prospective BLINDSCE cohort.GeroScience · 2026Article
- Intrinsic capacity across the adult lifespan in China: baseline analysis from the nationwide longitudinal PENG ZU cohort.GeroScience · 2026Article
- Are levels of DHEAS indicative of subjective health - results of the population-based longitudinal CARLA study.npj aging · 2026Article
- Article
- Development and Validation of the Healthy Longevity Index for Personalized Healthy Aging in Primary Care: Cross-National Retrospective Analysis.JMIR aging · 2025Article
- Research progress on intrinsic capacity in older adults: Concepts, epidemiology, assessments, influencing factors, adverse outcomes, and interventions.Global health & medicine · 2025Review
- Muscle-Specific Strength Better Predicts Physical Performance Decline Than Conventional Metrics: The I-Lan Longitudinal Aging Study.Journal of cachexia, sarcopenia and muscle · 2025Article
- Intrinsic Capacity Predictors of Dementia and Mortality in the Sydney Memory and Ageing Study.International journal of geriatric psychiatry · 2025Article
- Healthy aging: how does a multidimensional construct of functional ability predict objective and subjective outcomes?BMC geriatrics · 2025Article
- A blood-based epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and lifestyle factors.Nature aging · 2025Article
- Determinants of intrinsic capacity among older adults in low- and middle-income countries: A scoping review.Belitung nursing journal · 2025Review
- Intrinsic capacity transitions predict overall and cause-specific mortality, incident disability, and healthcare utilization.The journal of nutrition, health & aging · 2024Article
- Safeguarding vitality and cognition: The role of sarcopenia in intrinsic capacity decline among octogenarians from multiple cohorts.The journal of nutrition, health & aging · 2024Article
- Dose-Responsive Impacts of Social Frailty on Intrinsic Capacity and Healthy Aging among Community-Dwelling Middle-aged and Older Adults: Stronger Roles of Social Determinants over Biomarkers.The Journal of frailty & aging · 2024Article
- Long-Term Mortality Risk in Older Adults with Sarcopenia: An 11-Year Prospective Cohort Study Comparing AWGS 2014 and AWGS 2019 Guidelines for Enhanced Clinical Utility and Accurate Risk Prediction.The journal of nutrition, health & aging · 2023Article
- Comparative Analysis of Intrinsic Capacity Impairments, Determinants, and Clinical Consequences in Older Community-Dwellers in Japan and Taiwan: Longitudinal Studies Showing Shared Traits and Distinct Presentations.The journal of nutrition, health & aging · 2023Observational
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to explore the biological features and mortality risk of intrinsic capacity (IC) and functional ability (FA). Based on data from 1839 participants from the I-Lan Longitudinal Aging Study, multivariable Cox proportional hazard models were used to evaluate the predictive ability of IC (range 0-100) and FA (range 0-100) on 10-year mortality. Of 2038 repeated measurements for IC within a 7-year observational period, multivariable logistic regression was used to compare biological features of participants with maintained, improved and rapidly deteriorated IC. A 1-point increased IC value was associated with a 5% (HR 0.95, 95% CI 0.93-0.97,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.