Evidence map›Paper›PMID 36749768›Full record

ArticlePloS one2023

Atrial fibrillation in UK South Asian hospitalized ischemic stroke patients: The BRAINS study.

Taylor Aurelius, Gie Ken-Dror, Sapna D Sharma, Sageet Amlani, Gunaratnam Gunathilagan, David L Cohen, Chakravarthi Rajkumar, Stuart Maguire, Sissi Ispoglou, Ibrahim Balogun and 12 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Observational
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 20 institutions in 1 country.

Taylor AureliusInstitute of Cardiovascular Research Royal Holloway, University of London (ICR2UL), London, United Kingdom.ORCID 0000-0001-5925-1910
Gie Ken-DrorInstitute of Cardiovascular Research Royal Holloway, University of London (ICR2UL), London, United Kingdom.
Sapna D SharmaInstitute of Cardiovascular Research Royal Holloway, University of London (ICR2UL), London, United Kingdom.
Sageet AmlaniBARTS and the London NHS Trust/ Royal London Hospital, London, United Kingdom.
Gunaratnam GunathilaganQueen Elizabeth the Queen Mother Hospital, Kent, United Kingdom.
David L CohenNorthwick Park Hospital, London, United Kingdom.
Chakravarthi RajkumarBrighton and Sussex University Hospitals NHS Trust & Brighton and Sussex Medical School, University of Sussex, Sussex, United Kingdom.
Stuart MaguireBradford Teaching Hospital, West Yorkshire, United Kingdom.
Sissi IspoglouCity Hospital Birmingham, West Midlands, United Kingdom.
Ibrahim BalogunWilliam Harvey Hospital, Kent, United Kingdom.
Anthea ParryHillingdon Hospital, London, United Kingdom.
Lakshmanan SekaranLuton and Dunstable Hospital, Bedfordshire, United Kingdom.
Hafiz SyedNewham University Hospital, London, United Kingdom.
Enas LawrenceCroydon University Hospital, London, United Kingdom.
Ravneeta SinghWest Middlesex University, London, United Kingdom.
Ahamad HassanLeeds General Infirmary, West Yorkshire, United Kingdom.
Chris WhartonNew Cross Hospital, West Midlands, United Kingdom.
Khalid JavaidWalsall Manor Hospital, West Midlands, United Kingdom.
Neetish GoorahQueen's Park Hospital Royal Blackburn, Lancashire, United Kingdom.
Peter CarrBirmingham Heartlands Hospital, West Midlands, United Kingdom.
Eman Abdus SamiAiredale General Hospital, West Yorkshire, United Kingdom.
Pankaj SharmaInstitute of Cardiovascular Research Royal Holloway, University of London (ICR2UL), London, United Kingdom.ORCID 0000-0003-3641-7441
Royal Holloway University of London · GBAiredale General Hospital · GBBirmingham City Hospital · GBBradford Teaching Hospitals NHS Foundation Trust · GBBrighton and Sussex Medical School · GBCroydon University Hospital · GBHeartlands Hospital · GBHillingdon Hospital · GBImperial College Healthcare NHS Trust · GBLeeds General Infirmary · GBLuton and Dunstable Hospital · GBNew Cross Hospital · GBNewham University Hospital · GBNorthwick Park Hospital · GBQueen Elizabeth the Queen Mother Hospital · GBRoyal London Hospital · GBUniversity of Ulster · GBWalsall Manor Hospital · GBWest Middlesex University Hospital · GBWilliam Harvey Hospital · GB

Funding

Department of Health
6 · The paper itself

Abstract

introductionSouth Asian diaspora comprise one of the largest ethnic minority groups in the world yet data about atrial fibrillation (AF) in this demographic is understudied. Our aim is to identify differences in AF prevalence and treatment between South Asians and white British stroke patients.

methodThe UK arm of a prospective ongoing large international repository on stroke was analysed. Ethnic differences in AF prevalence and management in those with ischemic stroke were analysed.

resultsOf the 3515 individuals recruited with ischemic stroke, 1482 (men: 972, women: 510) were South Asian and 2033 (men:1141, women:892) of white British ethnicity. AF was present in 462 white British and 193 South Asians stroke patients, with South Asians displaying a lower prevalence of AF (South Asians: 13.0% vs white British 22.7%, P<0.001). Despite adjustment for traditional AF risk factors, South Asians had a significantly lower OR of AF compared to white British stroke patients (OR: 0.40, 95%CI: 0.33:0.49, P<0.001). Among confirmed AF cases, 31.8% of South Asians and 41.4% of white British were untreated at admission (P = 0.02). Antiplatelet treatment was significantly higher among South Asians at both admission (South Asian: 47.4% vs. white British: 29.9%, P<0.001) and discharge (South Asian: 49.5% vs. white British: 34.7%, P = 0.001), although anticoagulation treatment was similar across both ethnic groups at admission (South Asian: 28.5% vs white British: 28.1%, P = 0.93), and discharge (South Asian: 45.1% vs white British: 43.1%, P = 0.64).

conclusionStroke patients of South Asian descent are at significantly lower risk of AF but more likely to be on antiplatelet treatment compared to their white British counterparts.

Indexed as

Atrial FibrillationIschemic StrokeStrokeEthnicityFemaleHumansMaleMinority GroupsProspective StudiesRisk FactorsUnited Kingdom

Identifiers

PMID36749768
PMCPMC9904493
OpenAlexW4319333357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.