Evidence map›Paper›PMID 36749650›Full record

ArticleJMIR diabetes2023

The Effectiveness of an App (Insulia) in Recommending Basal Insulin Doses for French Patients With Type 2 Diabetes Mellitus: Longitudinal Observational Study.

Camille Nevoret, Nathalie Gervaise, Brigitte Delemer, Said Bekka, Bruno Detournay, Amine Benkhelil, Amar Bahloul, Geneviève d'Orsay, Alfred Penfornis

Open access · goldFull text read
In one paragraph

Article in JMIR diabetes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Basal insulin titration by the app.The Lancet regional health. Europe · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Camille Nevoret *Biostatistics Department, CEMKA, Bourg-la-Reine, France.ORCID https://orcid.org/0000-0002-5485-1535
Nathalie GervaiseDiabetology Department, Clinique NCT+, Tours, France.ORCID https://orcid.org/0000-0001-9330-0341
Brigitte Delemer *Endocrinology, Diabetology and Nutrition Department, Robert Debre University Hospital, Reims, France.ORCID https://orcid.org/0000-0002-4320-2601
Said BekkaInstitut de Diabétologie et Nutrition du Centre, Mainvilliers, France.ORCID https://orcid.org/0000-0001-7520-7493
Bruno Detournay *Biostatistics Department, CEMKA, Bourg-la-Reine, France.ORCID https://orcid.org/0000-0001-7843-4608
Amine Benkhelil *Diabetes Department, Sanofi France, Gentilly, France.ORCID https://orcid.org/0000-0003-4311-7543
Amar Bahloul *Diabetes Department, Sanofi France, Gentilly, France.ORCID https://orcid.org/0000-0003-4548-5059
Geneviève d'OrsayVoluntis SA, Suresnes, France.ORCID https://orcid.org/0000-0002-7392-0874
Alfred Penfornis *Endocrinology, Diabetology and Metabolic Diseases Department, Sud-Francilien Hospital, Université Paris-Saclay, Corbeil-Essonnes, France.ORCID https://orcid.org/0000-0002-9635-7674
Cemka-Eval (France) · FRSanofi (France) · FRHôpital Robert-Debré · FRUniversité Paris-Saclay · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFor patients with type 2 diabetes (T2D), calculating the daily dose of basal insulin may be challenging. Insulia is a digital remote monitoring solution that uses clinical algorithms to recommend basal insulin doses. A predecessor device was evaluated in the TeleDiab-2 randomized controlled trial, showing that a higher percentage of patients using the app achieved their target fasting blood glucose (FBG) level compared to the control group, and insulin doses were adjusted to higher levels without hypoglycemia.

objectiveThis study aims to analyze how the glycemic control of Insulia users has evolved when using the app in a real-life setting in France.

methodsA retrospective observational analysis of data collected through the device in adult French patients with T2D treated with basal insulin and oral antihyperglycemic agents using the system for ≥6 months was conducted. Analyses were descriptive and distinguished the results in a subpopulation of regular and compliant users of the app. Glycemic outcomes were estimated considering the percentage of patients who achieved their individualized FBG target between 5.5 and 6 months following the initiation of device use, the frequency of hypoglycemia resulting in a treatment change over the 6-month period of exposure, and the evolution of the average hemoglobin A

resultsOf the 484 users, 373 (77.1%) performed at least one dose calculation. A total of 221 (59.2%) users were men. When app use started, the mean age, BMI, HbA

conclusionsAn improvement in glycemic control as measured by the percentage of patients reaching their FBG individualized target range without increasing hypoglycemic risk was observed in patients using the Insulia app, especially among regular users following the dose recommendations of the algorithm.

Indexed as

clinical algorithmdiabetes mellitusdigital monitoringhealth appinsulinmedical informatics appsmobile healthmobile health interventionremote monitoringtelemedicinevirtual care

Identifiers

PMID36749650
PMCPMC10018375
OpenAlexW4319156410

What OpenQuestion holds

Textfull text, public
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.