ArticleBrain and behavior2023
Predicted resting metabolic rate and prognosis in patients with ischemic stroke.
Article in Brain and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- Predicted resting metabolic rate and prognosis in patients with ischemic stroke.Brain and behavior · 2023Article
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6 authors at 3 institutions in 1 country.
Funding
Abstract
purposeResting metabolic rate (RMR) could represent metabolic health status. This study aims to examine the association of the predicted RMR with 1-year poor functional outcome and all-cause mortality in patients with ischemic stroke as a proxy of metabolic profile.
methodsA total of 15,166 patients with ischemic stroke or transient ischemic attack (TIA) from the Third China National Stroke Registry (CNSR-III) were enrolled in this study. The Harris-Benedict equation based on sex, age, weight, and height was used to predict RMR. The primary endpoints were poor functional outcome defined as ≥3 modified Rankin Scale (mRS) score and all-cause mortality within 1 year. The association between predicted RMR and prognosis was assessed by multivariable regression analysis. Besides that, subgroup analysis of age, sex, and body mass index (BMI) with predicted RMR was also performed.
results12.85% (1657) individuals had poor functional outcome and 2.87% (380) died of whatever causes within 1 year. An inverse association was found between predicted RMR with poor functional outcome and all-cause mortality. Compared to the lowest quartile, the highest quartile was significantly associated with lower risk of poor functional outcome (adjusted odds ratio [OR], 0.43 [95% confidence interval (CI) 0.33-0.56]) and all-cause mortality (adjusted hazard ratio [HR], 0.44 [95% CI 0.28-0.71]). No significant interaction was between predicted RMR and specified subgroup.
conclusionsPredicted RMR by the Harris-Benedict equation seems to be an independent protective predictor of poor functional outcome and all-cause mortality after ischemic stroke as a metabolic proxy.
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