Evidence map›Paper›PMID 36749583›Full record

ArticleAmerican journal of respiratory cell and molecular biology2023

AKT Phosphorylates FAM13A and Promotes Its Degradation via CUL4A/DDB1/DCAF1 E3 Complex.

Lu Gong, Samuel Bates, Yujun Li, Xin Lin, Wenyi Wei, Xiaobo Zhou

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. 1-L Transcription in Prion Diseases.International journal of molecular sciences · 2024
    Article
  5. The FAM13A Long Isoform Regulates Cilia Movement and Coordination in Airway Mucociliary Transport.American journal of respiratory cell and molecular biology · 2024
    Article
  6. Breathing new life into the study of COPD with genes identified from genome-wide association studies.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lu GongChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Samuel BatesChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Yujun LiChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Xin LinChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Wenyi WeiDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Xiaobo ZhouChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0002-7127-2869
Brigham and Women's Hospital · USBeth Israel Deaconess Medical Center · US

Funding

Metabolic Control of Stemness in lung epithelial progenitors by FAM13AR01HL127200 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ZHOU, ANNY XIAOBO · 2015 to 2024
$4.9M
Integrative Characterization on the function of COPD GWAS gene, HHIPR01HL148667 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEI, WENYI, ZHOU, ANNY XIAOBO · 2020 to 2023
$2.6M
NHLBI NIH HHS R01 HL127200NHLBI NIH HHS R01 HL148667NIH HHS R01HL127200NIH HHS R01HL148667
6 · The paper itself

Abstract

SNPs within

Indexed as

Proto-Oncogene Proteins c-aktPulmonary Disease, Chronic ObstructiveAnimalsDNA-Binding ProteinsGenome-Wide Association StudyLungMiceUbiquitin-Protein LigasesDdb1 protein, mouseDNA-Binding ProteinsProto-Oncogene Proteins c-aktUbiquitin-Protein LigasesAKTcellular responseE3 ligaseFAM13Aprotein degradation

Identifiers

PMID36749583
PMCPMC10174174
OpenAlexW4319333949

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.