Evidence map›Paper›PMID 36749539›Full record

ReviewHuman cell2023

Emergence of monkeypox: a worldwide public health crisis.

J P Shabaaz Begum, Leirika Ngangom, Prabhakar Semwal, Sakshi Painuli, Rohit Sharma, Ashim Gupta

Abstract readReview
In one paragraph

Review in Human cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Mpox Airborne Transmission: A Systematic Review.Reviews in medical virology · 2026
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Monkeypox (Mpox): Diagnosis and Emerging Challenges.The Yale journal of biology and medicine · 2024
    Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Monkeypox Virus (MPXV) Infection: A Review.Infectious disorders drug targets · 2024
    Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

J P Shabaaz Begum *Department of Life Sciences, Graphic Era (Deemed to Be University), Dehradun, Uttarakhand, 248002, India.ORCID http://orcid.org/0000-0003-4941-5517
Leirika Ngangom *Department of Life Sciences, Graphic Era (Deemed to Be University), Dehradun, Uttarakhand, 248002, India.ORCID http://orcid.org/0000-0002-8123-994X
Prabhakar Semwal *Department of Life Sciences, Graphic Era (Deemed to Be University), Dehradun, Uttarakhand, 248002, India.ORCID http://orcid.org/0000-0001-5137-5169
Sakshi PainuliUttarakhand Council for Biotechnology (UCB), Prem Nagar, Dehradun, Uttarakhand, 248007, India.ORCID http://orcid.org/0000-0002-8941-2006
Rohit SharmaFaculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, 221005, India.ORCID http://orcid.org/0000-0002-3682-3573
Ashim GuptaFuture Biologics, Lawrenceville, GA, 30043, USA. ashim6786@gmail.com.ORCID http://orcid.org/0000-0003-1224-2755

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human monkeypox virus (MPV), a zoonotic illness that was hitherto solely prevalent in Central and West Africa, has lately been discovered to infect people all over the world and has become a major threat to global health. Humans unintentionally contract this zoonotic orthopoxvirus, which resembles smallpox, when they come into contact with infected animals. Studies show that the illness can also be transferred through frequent proximity, respiratory droplets, and household linens such as towels and bedding. However, MPV infection does not presently have a specified therapy. Smallpox vaccinations provide cross-protection against MPV because of antigenic similarities. Despite scant knowledge of the genesis, epidemiology, and ecology of the illness, the incidence and geographic distribution of monkeypox outbreaks have grown recently. Polymerase chain reaction technique on lesion specimens can be used to detect MPV. Vaccines like ACAM2000, vaccinia immune globulin intravenous (VIG-IV), and JYNNEOS (brand name: Imvamune or Imvanex) as well as FDA-approved antiviral medications such as brincidofovir (brand name: Tembexa), tecovirimat (brand name: TPOXX or ST-246), and cidofovir (brand name: Vistide) are used as therapeutic medications against MPV. In this overview, we provide an outline of the MPV's morphology, evolution, mechanism, transmission, diagnosis, preventative measures, and therapeutic approaches. This study offers the fundamental information required to prevent and manage any further spread of this emerging virus.

Indexed as

Mpox, MonkeypoxSmallpoxAnimalsCidofovirGlobal HealthHumansPublic HealthVaccinationCidofovirAntiviral medicationsMonkeypox virusOrthopoxvirusesOutbreakPandemicVaccination

Identifiers

PMID36749539
PMCPMC9903284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.