Evidence map›Paper›PMID 36749535›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2023

Canine distemper virus and canine adenovirus type 1 co-infection in a free-living hoary fox (Lycalopex vetulus) from Brazil.

Maraya Lincoln Silva, Mayara Grego Caiaffa, André Luiz Mota da Costa, Rodrigo Hidalgo Friciello Teixeira, Ticiana Brasil Ervedosa, Eduardo Ferreira Machado, Pedro Enrique Navas Suárez, Rodrigo Albergaria Réssio, Cinthya Cirqueira Borges, Isis Paixão de Jesus and 6 more

Open access · greenAbstract readCase Reports
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Molecular Detection of Viral and Bacterial Pathogens in Red Foxes (Animals : an open access journal from MDPI · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Maraya Lincoln SilvaParque Zoológico Municipal Quinzinho de Barros, Rua Teodoro Kaisel, 883 - Vila Hortência, Sorocaba - SP, Sorocaba, São Paulo, 18020268, Brazil.ORCID http://orcid.org/0000-0003-4335-0855
Mayara Grego CaiaffaParque Zoológico Municipal Quinzinho de Barros, Rua Teodoro Kaisel, 883 - Vila Hortência, Sorocaba - SP, Sorocaba, São Paulo, 18020268, Brazil.ORCID http://orcid.org/0000-0003-4972-7115
André Luiz Mota da CostaParque Zoológico Municipal Quinzinho de Barros, Rua Teodoro Kaisel, 883 - Vila Hortência, Sorocaba - SP, Sorocaba, São Paulo, 18020268, Brazil.ORCID http://orcid.org/0000-0002-3913-0123
Rodrigo Hidalgo Friciello TeixeiraParque Zoológico Municipal Quinzinho de Barros, Rua Teodoro Kaisel, 883 - Vila Hortência, Sorocaba - SP, Sorocaba, São Paulo, 18020268, Brazil.ORCID http://orcid.org/0000-0001-8219-0845
Ticiana Brasil ErvedosaCentro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil.ORCID http://orcid.org/0000-0003-4148-4315
Eduardo Ferreira MachadoCentro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil.ORCID http://orcid.org/0000-0002-4610-7490
Pedro Enrique Navas SuárezCentro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil.ORCID http://orcid.org/0000-0003-1385-901X
Rodrigo Albergaria RéssioCentro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil.ORCID http://orcid.org/0000-0003-4682-5326
Cinthya Cirqueira BorgesCentro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil.ORCID http://orcid.org/0000-0002-3719-5505
Isis Paixão de JesusCentro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil.ORCID http://orcid.org/0000-0002-4874-4522
Julia de CarvalhoCentro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil.ORCID http://orcid.org/0000-0001-9791-0016
Ketlyn Bolsachini FigueiredoCentro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil.
Ana Carolina Souza Ramos de CarvalhoCentro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil.
Paulo Eduardo BrandãoLaboratório de Zoonoses Virais, Medicina Veterinária Preventiva E Saúde Animal, Faculdade de Veterinária E Zootecnia, Universidade de São Paulo, Avenida Professor Orlando Marques de Paiva, 70, São Paulo, SP, 05508270, Brazil.ORCID http://orcid.org/0000-0003-0213-7839
Natália Coelho Couto de Azevedo FernandesCentro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil.ORCID http://orcid.org/0000-0003-4754-4200
Juliana Mariotti GuerraCentro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil. jumariotti.vet@gmail.com.ORCID http://orcid.org/0000-0002-0326-7187
Instituto Adolfo Lutz · BRUniversidade de São Paulo · BRUniversidade de Sorocaba · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 404510/2021-3FESIMA 28/2020
6 · The paper itself

Abstract

The present case is the first description of a co-infection with canine distemper virus (CDV) and canine adenovirus type 1 (CAdV-1) in a free-living hoary fox pup from Brazil. The animal was found and rescued with poor body condition, dehydration, incoordination, ataxia, excessive vocalization, and "blue eyes" phenomenon. Despite the efforts, euthanasia was elected due to worsening clinical signs and poor prognosis. Pathologic examination revealed a mild, acute, random, necrotizing hepatitis, acute bronchopneumonia, hydrocephalus, corneal edema with epithelium degeneration, and acidophilic intracytoplasmatic inclusion bodies in different epithelial cells types with rare syncytial. Through immunohistochemistry, CDV antigen was observed in the tongue, trachea, lungs, liver, spleen, stomach, intestine and urinary bladder. Adenovirus antigen was identified in the nucleus of scattered hepatocytes. Polymerase chain reaction and sequencing demonstrated high similarity with CAdV-1 and wild-type strain of CDV close related to Brazilian viral lineages isolated from domestic dogs. Disease surveillance in wildlife animals is essential to assess possible conservation threats and consider the implementation of mitigation or control measures.

Indexed as

Adenoviruses, CanineCoinfectionDistemperDistemper Virus, CanineAnimalsBrazilDogsFoxesCanine mastadenovirus ACanine morbillivirusHistopathologyImmunohistochemistryMolecular biology

Identifiers

PMID36749535
PMCPMC9943989
OpenAlexW4319334275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.