ArticleGeroScience2023
The cerebellum is causally involved in episodic memory under aging.
Article in GeroScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Review and Meta-analysis of the Neural Correlates of Direct vs. Generative Retrieval of Episodic Autobiographical Memory.Neuropsychology review · 2025Pooled it
- A bias-accounting meta-analytic approach refines and expands the cerebellar behavioral topography.Neuroscience and biobehavioral reviews · 2025Pooled it
- Effects of Fermented Soy on Cognition in Older Adults: Outcomes of a Randomized, Controlled Trial.Nutrients · 2025Trial
- Temporal Interference Modulates Medial Temporal and Frontoparietal Activity During Mnemonic Discrimination: A High-Resolution Whole-Brain fMRI Investigation.Hippocampus · 2026Article
- Cerebellar Atrophy Modulates Freezing of Gait in Multiple System Atrophy Through Cognitive Dysfunction.CNS neuroscience & therapeutics · 2026Article
- Cerebellar cognitive affective syndrome (Schmahmann syndrome) following isolated cerebellar infarction.Dementia & neuropsychologia · 2026Article
- Cerebellar subregional structural changes across the Alzheimer's disease continuum: a longitudinal analysis of cognitive and behavioural correlates.Brain communications · 2026Article
- The emerging role of multiomics in aging research.Epigenomics · 2025Review
- Alzheimer's disease cerebrospinal fluid biomarker levels and APOE genetic status are associated with hippocampal-cerebellar functional connectivity.Neurobiology of aging · 2025Article
- A bias-accounting meta-analytic approach refines and expands the cerebellar behavioral topography.bioRxiv : the preprint server for biology · 2025Article
- Neurocognition, cerebellar functions and psychiatric features in spinocerebellar ataxia type 34: a case series.Frontiers in computational neuroscience · 2025Article
- The Impact of Ageing on Episodic Memory Retrieval: How Valence Influences Neural Functional Connectivity.NeuroSci · 2024Article
- Are we really targeting and stimulating DLPFC by placing transcranial electrical stimulation (tES) electrodes over F3/F4?Human brain mapping · 2023Article
- Imaging the cerebellum in post-traumatic stress and anxiety disorders: a mini-review.Frontiers in systems neuroscience · 2023Review
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
Episodic memory decline is a major signature of both normal and pathological aging. Many neural regions have been implicated in the processes subserving both episodic memory and typical aging decline. Here, we demonstrate that the cerebellum is causally involved episodic memory under aging. We show that a 12-day neurostimulation program delivered to the right cerebellum led to improvements in episodic memory performance under healthy aging that long outlast the stimulation period - healthy elderly individuals show episodic memory improvement both immediately after the intervention program and in a 4-month follow-up. These results demonstrate the causal relevance of the cerebellum in processes associated with long-term episodic memory, potentially highlighting its role in regulating and maintaining cognitive processing. Moreover, they point to the importance of non-pharmacological interventions that prevent or diminish cognitive decline in healthy aging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.