Evidence map›Paper›PMID 36749418›Full record

SynthesisClinical research in cardiology : official journal of the German Cardiac Society2023

Comparison of plug-based versus suture-based vascular closure for large-bore arterial access: a collaborative meta-analysis of observational and randomized studies.

Oliver Dumpies, Alexander Jobs, Danilo Obradovic, Maarten van Wiechen, Philipp Hartung, Johannes Rotta Detto Loria, Johannes Wilde, Nicolas Majunke, Philipp Kiefer, Thilo Noack and 4 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in Clinical research in cardiology : official journal of the German Cardiac Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Suture-based versus plug-based closure for large-bore arterial access: an individual patient-level meta-analysis of randomised trials.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. The great debate in vascular closure: a meta-analysis points to a clear winner.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Article
  7. Percutaneous Cannulation for Minimally Invasive Heart Valve Surgery: Results from a Multicenter Registry.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  8. Ipsilateral Safety Wire as Bailout for MANTA Failure in Patients Undergoing Transcatheter Aortic Valve Replacement.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  9. Impact of Sheath Type on Vascular and Bleeding Complications After Transcatheter Aortic Valve Replacement: A Post Hoc Analysis From the MARVEL Registry Study.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Observational
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Oliver DumpiesDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Alexander JobsDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Danilo ObradovicDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Maarten van WiechenDepartment of Cardiology, Erasmus University Medical Center, Rotterdam, Netherlands.
Philipp HartungDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Johannes Rotta Detto LoriaDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Johannes WildeDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Nicolas MajunkeDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Philipp KieferDepartment of Cardiac Surgery, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Thilo NoackDepartment of Cardiac Surgery, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Holger ThieleDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Nicolas van MieghemDepartment of Cardiology, Erasmus University Medical Center, Rotterdam, Netherlands.
Steffen DeschDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Mohamed Abdel-WahabDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany. mohamed.abdel-wahab@medizin.uni-leipzig.de.ORCID http://orcid.org/0000-0002-9596-558X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLarge-bore arteriotomies can be percutaneously closed with suture-based or plug-based vascular closure device (VCD) strategies. The efficacy of both techniques remains controversial.

aimsWe conducted a meta-analysis of comparative studies between both VCD strategies, focusing on the most commonly applied VCDs (MANTA and ProGlide).

methodsWe searched MEDLINE, the Cochrane Central Register of Controlled Trials and Google scholar for observational studies (OS) and randomized controlled trials (RCT) comparing vascular closure with the MANTA-based and the ProGlide-based technique. The principal endpoint of this analysis was access-site related vascular complications. Both study types were analyzed separately.

resultsAccess-site related vascular complications were less frequent after vascular closure with the MANTA technique in the analysis of OS (RR 0.61 [95%CI 0.43-0.89], p = 0.01, I

conclusionsWhile OS point to favorable outcomes for large-bore vascular closure with the MANTA-based technique, RCT data show that this strategy is associated with more access-site related vascular complications as well as endovascular stenting or vascular surgery due to device failure compared with the ProGlide-based technique.

Indexed as

Cardiovascular DiseasesVascular Closure DevicesFemoral ArteryHemorrhageHemostatic TechniquesHumansObservational Studies as TopicRandomized Controlled Trials as TopicTreatment OutcomeVascular Surgical ProceduresLarge-bore vascular closureMANTAProGlideVascular closure deviceVascular complications

Identifiers

PMID36749418
PMCPMC10160216

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.