SynthesisZeitschrift fur Rheumatologie2024
Systematic review to estimate the prevalence of inflammatory rheumatic diseases in Germany.
Synthesis in Zeitschrift fur Rheumatologie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Potential of digital applications for self-management and other outcomes in inflammatory rheumatic diseases: a systematic literature review.Frontiers in medicine · 2025Pooled it
- Digital Psychological Intervention for Inflammatory Rheumatic Diseases: A Pilot Randomized Clinical Trial.JAMA network open · 2025Trial
- [Rheuma-VOR-Health economic evaluation of early rheumatological diagnosis : Summary of the G-BA report].Zeitschrift fur Rheumatologie · 2026Article
- [Epidemiology and manifestations of Sjögren's disease].Zeitschrift fur Rheumatologie · 2026Article
- Observational
- Machine learning improves online self-referral for inflammatory rheumatic diseases: a registry-based validation study.Rheumatology international · 2026Article
- Medical Photography for Scientific Publishing (MedPhotoPubl) in Rheumatology and Rehabilitation.Journal of Korean medical science · 2026Review
- [Survey on primary care for rheumatology patients in Lower Franconia and the contribution of digital health].Zeitschrift fur Rheumatologie · 2026Article
- Prevalence and occupational risk of hip osteoarthritis and rotator cuff lesions - claims data analysis.International journal of occupational medicine and environmental health · 2026Article
- Frequency, diagnosis, and pharmacological treatment of giant cell arteritis in Germany: database analysis of medical insurance data.Therapeutic advances in musculoskeletal disease · 2026Article
- Prevalence and Incidence of Sjögren's Disease in Alaska Native and American Indian Peoples of Alaska.Arthritis care & research · 2025Article
- Frequency, diagnosis, and management of polymyalgia rheumatica in Germany-database analysis of medical insurance data.Rheumatology (Oxford, England) · 2025Article
- Effects of Multimodal Rheumatologic Complex Treatment in Childhood and Adolescence.Children (Basel, Switzerland) · 2025Article
- Real-World Prevalence, Incidence and Management of Systemic Lupus Erythematosus in Germany: A Retrospective Claims Data Analysis.Rheumatology and therapy · 2025Article
- Sex-specific and regional differences in the prevalence of diagnosed autoimmune diseases in Germany, 2022.Research in health services & regions · 2025Article
- ActiLup: is it feasible? High-intensity interval training in systemic lupus erythematosus patients with fatigue: protocol for a prospective, monocentric proof-of-concept study.BMJ open sport & exercise medicine · 2025Article
- Complement proteins in axial spondyloarthritis: associations with disease activity and TNFi treatment response in a multicentre RCT.Rheumatology advances in practice · 2025Article
- Article
- Article
- Level and correlates of physical activity among children and adolescents with juvenile idiopathic arthritis compared to controls: results from a German nationwide prospective observational cohort study.Pediatric rheumatology online journal · 2024Observational
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to update the prevalence estimates of inflammatory rheumatic diseases (IRD) in Germany.
methodsA systematic literature search in PubMed and Web of Science (last search 08 November 2022) identified original articles (regional and nationwide surveys and claims data analyses for arthritides, connective tissue diseases, and vasculitides) on prevalences for the period 2014-2022. Data sources, collection period, case definition, and risk of bias are reported. Prevalences were estimated from available national data, with consideration of international data.
resultsScreening by two authors yielded 263 hits, of which 18 claims data analyses and 2 surveys met the inclusion criteria. Prevalences ranged from 0.42 to 1.85% (rheumatoid arthritis), 0.32-0.5% (ankylosing spondylitis), 0.11-0.32% (psoriatic arthritis), 0.037-0.14% (systemic lupus erythematosus), 0.07-0.77% (Sjögren's disease/sicca syndrome), 0.14-0.15% (polymyalgia rheumatica, ≥ 40 years), 0.04-0.05% (giant cell arteritis, ≥ 50 years), and 0.015-0.026% (ANCA-associated vasculitis). The risk of bias was moderate in 13 and high in 7 studies. Based on the results, we estimate the prevalence of IRD in Germany to be 2.2-3.0%, which corresponds to approximately 1.5-2.1 million affected individuals. The prevalence of juvenile idiopathic arthritis was reported to be around 0.10% (0.07-0.10%) of 0-18-year-olds, corresponding to about 14,000 children and adolescents in Germany.
conclusionThis systematic review shows an increase in the prevalence of IRD in Germany, which is almost exclusively based on claims data analyses. In the absence of multistage population studies, the available data are, overall, uncertain sources for prevalence estimates, with a moderate to high risk of bias.
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