ArticleHeadache2023
Depression and anxiety in women with idiopathic intracranial hypertension compared to migraine: A matched controlled cohort study.
Article in Headache, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Smoking and idiopathic intracranial hypertension: a meta-analysis.Eye (London, England) · 2026Pooled it
- Article
- Idiopathic intracranial hypertension presenting with obsessive thoughts: a rare neuropsychiatric manifestation "case report".BMC neurology · 2026Article
- Long-term headaches in children with idiopathic intracranial hypertension-a 10 years follow-up.Frontiers in pediatrics · 2026Article
- Cognitive impairment in idiopathic intracranial hypertension: A conceptual framework and therapeutic implications.Surgical neurology international · 2026Review
- Idiopathic Intracranial Hypertension in Children and Adolescents with Obesity: A Narrative Review.Children (Basel, Switzerland) · 2025Review
- Longitudinal Visual Outcomes and Risk of Papilledema Recurrence in Fulminant Idiopathic Intracranial Hypertension.Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · 2025Article
- Clinical outcomes of bariatric surgery in patients with obesity and idiopathic intracranial hypertension.Surgical endoscopy · 2025Article
- The Psychological and Cognitive Landscape of Adult Idiopathic Intracranial Hypertension: A Scoping Review.Neurology. Clinical practice · 2024Article
- Disability and Patient-Reported Satisfaction in Women with Idiopathic Intracranial Hypertension: A Comparative Study of Venous Sinus Stenting and Medical Management.Diagnostics (Basel, Switzerland) · 2024Article
- Progress and recognition of idiopathic intracranial hypertension: A narrative review.CNS neuroscience & therapeutics · 2024Review
- Managing idiopathic intracranial hypertension in the eye clinic.Eye (London, England) · 2024Review
- Idiopathic intracranial hypertension: a step change in understanding the disease mechanisms.Nature reviews. Neurology · 2023Review
- Depression and anxiety in women with idiopathic intracranial hypertension compared to migraine: A matched controlled cohort study.Headache · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo evaluate mental health burden in women with idiopathic intracranial hypertension (IIH) compared to matched women with migraine and population controls.
backgroundDepression and anxiety are recognized comorbid conditions in those with IIH and lead to worse predicted medical outcomes. The mental health burden in IIH has not been previously evaluated in a large, matched cohort study.
methodsWe performed a population-based matched, retrospective cohort study to explore mental health outcomes (depression and anxiety). We used data from IQVIA Medical Research Data, an anonymized, nationally representative primary care electronic medical records database in the United Kingdom, from January 1, 1995, to September 25, 2019. Women aged ≥16 years were eligible for inclusion. Women with IIH (exposure) were matched by age and body mass index with up to 10 control women without IIH but with migraine (migraine controls), and without IIH or migraine (population controls).
resultsA total of 3411 women with IIH, 30,879 migraine controls and 33,495 population controls were included. Of these, 237, 2372 and 1695 women with IIH, migraine controls and population controls, respectively, developed depression during follow-up, and 179, 1826 and 1197, respectively, developed anxiety. There was a greater hazard of depression and anxiety in IIH compared to population controls (adjusted hazard ratio [aHR] 1.38, 95% confidence interval [CI] 1.20-1.58; and aHR 1.40, 95% CI 1.19-1.64, respectively), while hazards were similar to migraine controls (aHR 0.98, 95% CI 0.86-1.13; and aHR 0.98, 95% CI 0.83-1.14, respectively).
conclusionDepression and anxiety burden in women with IIH is higher than in the general population, and comparable to that in matched women with migraine. This may indicate that presence of headache is a potential driver for comorbid depression and anxiety in IIH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.