Evidence map›Paper›PMID 36748455›Full record

ArticleHelicobacter2023

Helicobacter pylori treatment knowledge, access and barriers: A cross-sectional study.

Kimberly S Bailey, Heidi E Brown, Viktor Lekic, Kathi Pradeep, Juanita L Merchant, Robin B Harris

Open access · bronzeAbstract read
In one paragraph

Article in Helicobacter, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Knowledge, attitudes, and practices regardingFrontiers in public health · 2026
    Article
  6. Article
  7. Article
  8. Microorganisms · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Antibiotic Resistance Rates forMicroorganisms · 2023
    Article
  13. Epidemiology ofAntibiotics (Basel, Switzerland) · 2023
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kimberly S BaileyDepartment of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona, USA.
Heidi E BrownDepartment of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona, USA.ORCID https://orcid.org/0000-0001-8578-5510
Viktor LekicDepartment of Medicine, University of Arizona College of Medicine, Tucson, Arizona, USA.
Kathi PradeepDivision of Gastroenterology and Hepatology, Department of Medicine, University of Arizona College of Medicine, Tucson, Arizona, USA.
Juanita L MerchantDivision of Gastroenterology and Hepatology, Department of Medicine, University of Arizona College of Medicine, Tucson, Arizona, USA.
Robin B HarrisDepartment of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona, USA.
University of Arizona · US

Funding

SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI DEAN BILLHEIMER · 1994 to 2026
$36.7M
Training/Career Development and Education Core and PlansU54CA143925 · NCI · NORTHERN ARIZONA UNIVERSITY · PI JANI CHERI INGRAM, Jason A Wilder · 2009 to 2026
$27.5M
Uranium as an Environmental Risk Factor for Cancer Among the NavajoU54CA143924 · NCI · UNIVERSITY OF ARIZONA · PI Gloria D. Coronado · 2009 to 2026
$26.7M
MDSC Polarization and Helicobacter-Induced Gastric MetaplasiaR01DK118563 · NIDDK · UNIVERSITY OF ARIZONA · PI MERCHANT, JUANITA L. · 2018 to 2021
$1.4M
NCI NIH HHS U54 CA143924NCI NIH HHS U54 CA143925NIDDK NIH HHS R01 DK118563NIEHS NIH HHS P30 ES006694NIH HHS
6 · The paper itself

Abstract

backgroundHelicobacter pylori (Hp) is among the most common bacterial infections in the world and one of the most common infectious agents linked to malignancy, gastric cancer (GC). Within the US there is high disparity in the rates of Hp infection and associated diseases. Hp infection is treatable, and knowledge may influence screening and treatment seeking behaviors. MATERIALS AND

methodsIn this cross-sectional study of 1042 respondents recruited from the Online Amazon MTurk platform, we sought to assess baseline knowledge of Hp and to gain insight into barriers related to Hp care.

resultsJust over half (52.3%) reported some prior knowledge of Hp with 11.7% (n = 122) reporting being treated for Hp themselves and 21.4% reporting family members diagnosed with Hp. Of respondents reporting prior treatment, 95 (78%) reported GI upset and 27 (21%) reported not completing medications. Specific to Hp and GC, 70% indicated that a belief that the treatment was worse than the symptoms would affect their willingness to seek care, while 81% indicated knowing Hp can cause GC would affect their treatment decisions and knowing their gastric symptoms were caused by Hp would affect their willingness to receive care.

conclusionsKnowledge of Hp in this US sample of online respondents is low and self-reported difficulties with treatment compliance is high. Increasing awareness of this infection and addressing the challenges to treatment compliance could potentially reduce rates of Hp antibiotic resistance and progression to GC or other complications of Hp infection.

Indexed as

Helicobacter InfectionsHelicobacter pyloriStomach NeoplasmsCross-Sectional StudiesHumansattitudecompliancehelicobacter pyloriknowledgepractice

Identifiers

PMID36748455
PMCPMC10562139
OpenAlexW4319332910

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.