Evidence map›Paper›PMID 36748366›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2023

A stepwise external cardioversion protocol for atrial fibrillation to maximize acute success rate.

Yousef Darrat, Steve Leung, Liliane Elayi, Kevin Parrott, Gbolahan Ogunbayo, John Kotter, Vincent Sorrell, Vedant Gupta, Paul Anaya, Gustavo Morales and 3 more

Abstract read
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
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  3. Article
  4. Observational
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yousef DarratCardiac Electrophysiology Department, Saint Joseph Hospital, 1401 Harrodsburg Road, Lexington, KY 40504, USA.ORCID 0000-0003-1226-1227
Steve LeungDepartment of Internal Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY, USA.ORCID 0000-0003-2832-2258
Liliane ElayiCardiac Electrophysiology Department, Saint Joseph Hospital, 1401 Harrodsburg Road, Lexington, KY 40504, USA.
Kevin ParrottCardiac Electrophysiology Department, Baptist Health, Louisville, KY, USA.ORCID 0000-0002-7852-7369
Gbolahan OgunbayoDepartment of Internal Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY, USA.ORCID 0000-0002-4140-8067
John KotterDepartment of Internal Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY, USA.ORCID 0000-0001-6748-0617
Vincent SorrellDepartment of Internal Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY, USA.
Vedant GuptaDepartment of Internal Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY, USA.ORCID 0000-0002-0739-153X
Paul AnayaDepartment of Internal Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY, USA.ORCID 0000-0002-0441-8530
Gustavo MoralesCardiac Electrophysiology Department, Grandview Medical Center, Birmingham, AL, USA.ORCID 0000-0002-4032-3184
John CatanzarroDepartment of Internal Medicine, The University of Florida, Jacksonville, FL, USA.ORCID 0000-0001-5671-1125
Brian DelisleDepartment of Internal Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY, USA.ORCID 0000-0002-2146-327X
Claude S ElayiCardiac Electrophysiology Department, Saint Joseph Hospital, 1401 Harrodsburg Road, Lexington, KY 40504, USA.ORCID 0000-0002-2196-8788

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsCardioversion is a very commonly performed procedure for persistent atrial fibrillation (AF). However, there is no well-defined protocol to address failed external electrical direct current cardioversion. The aim of the study is to test the efficacy of a pre-defined stepwise cardioversion protocol for patients with persistent AF of ≤12 months. Success was the achievement of sinus rhythm. METHODS AND

resultsThe study population included patients with persistent AF of ≤12 months duration requiring rhythm management. Patients were offered cardioversion using a pre-defined stepwise protocol using different electrode placement locations, applying compression at end of expiration, and higher energy delivered simultaneously through two defibrillators. : A total of 414 patients were included in the study, of which 362 (87.4%) required a single successful cardioversion. The remaining 52 (12.5%) patients required additional cardioversion attempts using the stepwise cardioversion protocol with an overall success rate of 99.3%. Two simultaneous defibrillators were required in 14 patients (3.4%). Patients with multiple cardioversions (13.5%) experienced more local skin irritation and pain compared with patients with single cardioversion (13.5% vs. 3.5%, P = 0.004). The predictor for the need for multiple cardioversion attempts is high body mass index, while high transthoracic impedance is associated with failed cardioversion. No major complications were observed during the study.

conclusionThe stepwise cardioversion protocol has a high success rate of >99% and can be safely performed in outpatient or inpatient settings.

Indexed as

Atrial FibrillationBody Mass IndexElectric CountershockHumansRecurrenceTreatment OutcomeAtrial fibrillationExternal direct current cardioversionTransthoracic impedance

Identifiers

PMID36748366
PMCPMC10062296

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.