Evidence map›Paper›PMID 36748219›Full record

ArticleCardiovascular & hematological agents in medicinal chemistry2023

Ruoyu Wu, Linqi Zhang, Hongjun Xu, Hongxu Chen, Wei Zhao, Yongjie Zhou, Luyang Zhou, Jiangli Wu, Shengjun An

Open access · hybridAbstract read
In one paragraph

Article in Cardiovascular & hematological agents in medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ruoyu WuHebei Provincial Engineering Laboratory of Plant Bioreactor Preparation Technology, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China.
Linqi ZhangHebei Provincial Engineering Laboratory of Plant Bioreactor Preparation Technology, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China.
Hongjun XuHebei Provincial Engineering Laboratory of Plant Bioreactor Preparation Technology, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China.
Hongxu ChenHebei Provincial Engineering Laboratory of Plant Bioreactor Preparation Technology, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China.
Wei ZhaoHebei Provincial Engineering Laboratory of Plant Bioreactor Preparation Technology, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China.
Yongjie ZhouHebei Provincial Engineering Laboratory of Plant Bioreactor Preparation Technology, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China.
Luyang ZhouHebei Provincial Engineering Laboratory of Plant Bioreactor Preparation Technology, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China.
Jiangli WuHebei Provincial Engineering Laboratory of Plant Bioreactor Preparation Technology, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China.
Shengjun AnHebei Provincial Engineering Laboratory of Plant Bioreactor Preparation Technology, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China.
Hebei University of Chinese Medicine · CN

Funding

Hebei Province Science and Technology Support Program 213777100DNational Natural Science Foundation of China (NSFC) 82204658,81873230Natural Science Foundation of Hebei Province H2021423063,H2022423319
6 · The paper itself

Abstract

objective

methodsMale ApoE

resultsThe serum low-density lipoprotein cholesterol (LDL-C), triglyceride (TG), and total cholesterol (TC) levels were increased, and the high-density lipoprotein cholesterol (HDL-C) level was decreased in ApoE

conclusionThese findings indicated that SABP may exert an anti-atherosclerotic effect by lowering blood lipids and inhibiting inflammatory response via TLR4/ NF-κB signaling pathway.

Indexed as

AtherosclerosisCardiovascular DiseasesSalvia miltiorrhizaAnimalsApolipoproteins ECholesterolInterleukin-6LipidsMaleMiceMice, Inbred C57BLMice, Knockout, ApoENF-kappa BToll-Like Receptor 4Tumor Necrosis Factor-alphaApolipoproteins ECholesterolInterleukin-6LipidsNF-kappa BTlr4 protein, mouseToll-Like Receptor 4Tumor Necrosis Factor-alphaanti-inflammation atherosclerosisApoE<sup>-/-</sup> micecoronary arteries<i>Salvia miltiorrhiza</i>,aqueous extractTLR4/ NF-κB pathway

Identifiers

PMID36748219
PMCPMC10258915
OpenAlexW4319334273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.