Evidence map›Paper›PMID 36747850›Full record

ArticlebioRxiv : the preprint server for biology2023

Neural dynamics in the rodent motor cortex enables flexible control of vocal timing.

Arkarup Banerjee, Feng Chen, Shaul Druckmann, Michael A Long

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Arkarup BanerjeeNYU Neuroscience Institute, New York University Langone Health, New York, NY 10016, USA.
Feng ChenDepartment of Applied Physics, Stanford University, Stanford, CA 94305, USA.
Shaul DruckmannDepartment of Neuroscience, Stanford University, Stanford, CA 94304, USA.
Michael A LongNYU Neuroscience Institute, New York University Langone Health, New York, NY 10016, USA.
Cold Spring Harbor Laboratory · USStanford University · US

Funding

Neural Computations Underlying Vocal Sensorimotor TransformationsR01NS113071 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LONG, MICHAEL A · 2019 to 2023
$3.4M
NINDS NIH HHS R01 NS113071
6 · The paper itself

Abstract

Neocortical activity is thought to mediate voluntary control over vocal production, but the underlying neural mechanisms remain unclear. In a highly vocal rodent, the Alston's singing mouse, we investigate neural dynamics in the orofacial motor cortex (OMC), a structure critical for vocal behavior. We first describe neural activity that is modulated by component notes (approx. 100 ms), likely representing sensory feedback. At longer timescales, however, OMC neurons exhibit diverse and often persistent premotor firing patterns that stretch or compress with song duration (approx. 10 s). Using computational modeling, we demonstrate that such temporal scaling, acting via downstream motor production circuits, can enable vocal flexibility. These results provide a framework for studying hierarchical control circuits, a common design principle across many natural and artificial systems.

Identifiers

PMID36747850
PMCPMC9900850
OpenAlexW4317788342

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.