Evidence map›Paper›PMID 36747707›Full record

ArticlebioRxiv : the preprint server for biology2023

The memory of pathogenic IgE is contained within CD23

Miyo Ota, Kenneth B Hoehn, Takayuki Ota, Carlos J Aranda, Sara Friedman, Weslley F Braga, Alefiyah Malbari, Steven H Kleinstein, Scott H Sicherer, Maria A Curotto de Lafaille

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 11 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Miyo Ota
Sara Friedman
Steven H KleinsteinORCID 0000-0003-4957-1544
Maria A Curotto de LafailleORCID 0000-0002-3510-3777
Icahn School of Medicine at Mount Sinai · USYale University · USJanssen (United States) · USYork General Hospital · US

Funding

B cell memory in human food allergyR01AI153708 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CUROTTO DE LAFAILLE, MARIA A · 2021 to 2025
$3.8M
Heterogeneity of T cell phenotype and function in food allergyR01AI151707 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BERIN, CECILIA, CUROTTO DE LAFAILLE, MARIA A · 2020 to 2024
$3.7M
Cellular and molecular mechanisms of IgE cell memory in allergic responsesR01AI130343 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CUROTTO DE LAFAILLE, MARIA A, LAFAILLE, JUAN · 2017 to 2021
$2.9M
Computational mapping of human B cell migration and differentiation pathwaysK99AI159302 · NIAID · YALE UNIVERSITY · PI HOEHN, KENNETH · 2022 to 2022
$124k
NIAID NIH HHS K99 AI159302NIAID NIH HHS R01 AI130343NIAID NIH HHS R01 AI151707
6 · The paper itself

Abstract

Food allergy is caused by allergen-specific IgE antibodies but little is known about the B cell memory of persistent IgE responses. Here we describe in human pediatric peanut allergy CD23 One-Sentence Summary: We describe a unique population of IgG

Identifiers

PMID36747707
PMCPMC9900782
OpenAlexW4318034614

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.