Evidence map›Paper›PMID 36747681›Full record

ArticlebioRxiv : the preprint server for biology2023

Heterogeneity of the group B streptococcal type VII secretion system and influence on colonization of the female genital tract.

Brady L Spencer, Alyx M Job, Clare M Robertson, Zainab A Hameed, Camille Serchejian, Caitlin S Wiafe-Kwakye, Jéssica C Mendonça, Morgan A Apolonio, Prescilla E Nagao, Melody N Neely and 4 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 14 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Brady L SpencerUniversity of Colorado-Anschutz, Department of Immunology and Microbiology, Aurora, CO, USA.
Alyx M JobUniversity of Colorado-Anschutz, Department of Immunology and Microbiology, Aurora, CO, USA.
Clare M RobertsonDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
Zainab A HameedDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
Camille SerchejianDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
Caitlin S Wiafe-KwakyeUniversity of Maine, Molecular & Biomedical Sciences, Orono, ME, USA.
Jéssica C MendonçaUniversity of Colorado-Anschutz, Department of Immunology and Microbiology, Aurora, CO, USA.
Morgan A ApolonioUniversity of Colorado-Anschutz, Department of Immunology and Microbiology, Aurora, CO, USA.
Prescilla E NagaoRio de Janeiro State University, Roberto Alcantara Gomes Biology Institute, Rio de Janeiro, RJ, Brazil.
Melody N NeelyUniversity of Maine, Molecular & Biomedical Sciences, Orono, ME, USA.
Natalia KorotkovaDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky, Lexington, KY, USA.
Konstantin V KorotkovDepartment of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, USA.
Kathryn A PatrasDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
Kelly S DoranUniversity of Colorado-Anschutz, Department of Immunology and Microbiology, Aurora, CO, USA.
Baylor College of Medicine · USUniversity of Colorado Anschutz Medical Campus · USUniversidade do Estado do Rio de Janeiro · BRUniversity of Kentucky · USUniversity of Maine · USUniversity of Arizona · US

Funding

Host and bacterial mechanisms governing Group B streptococcal persistence in the female genital tractR01AI153332 · NIAID · UNIVERSITY OF COLORADO DENVER · PI DORAN, KELLY S · 2021 to 2025
$2.9M
Modulation of Blood-Brain Barrier Defense and Dysfunction during Bacterial MeningitisR01NS116716 · NINDS · UNIVERSITY OF COLORADO DENVER · PI DORAN, KELLY S · 2020 to 2024
$1.9M
Function of the type 7 secretion system in Group B StreptococcusR21AI169231 · NIAID · UNIVERSITY OF KENTUCKY · PI KOROTKOV, KONSTANTIN V, PATRAS, KATY · 2023 to 2024
$443k
The Role of Cas9 in Group B Streptococcal Colonization and DiseaseF32AI143203 · NIAID · UNIVERSITY OF COLORADO DENVER · PI SPENCER, BRADY L · 2020 to 2021
$134k
NIAID NIH HHS F32 AI143203NIAID NIH HHS R01 AI153332NIAID NIH HHS R21 AI169231NINDS NIH HHS R01 NS116716
6 · The paper itself

Abstract

Type VIIb secretion systems (T7SSb) in Gram-positive bacteria facilitate physiology, interbacterial competition, and/or virulence via EssC ATPase-driven secretion of small ɑ-helical proteins and toxins. Recently, we characterized T7SSb in group B

Identifiers

PMID36747681
PMCPMC9900821
OpenAlexW4318033708

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.