Evidence map›Paper›PMID 36747634›Full record

ArticlebioRxiv : the preprint server for biology2023

Engineered Antiviral Sensor Targets Infected Mosquitoes.

Elena Dalla Benetta, Adam J López-Denman, Hsing-Han Li, Reem A Masri, Daniel J Brogan, Michelle Bui, Ting Yang, Ming Li, Michael Dunn, Melissa J Klein and 8 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 8 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 3 countries.

Elena Dalla BenettaSchool of Biological Sciences, Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA, 92093, USA.
Adam J López-DenmanCSIRO Health and Biosecurity, Australian Centre for Disease Preparedness, Geelong, VIC 3220, AU.
Hsing-Han LiSchool of Biological Sciences, Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA, 92093, USA.
Reem A MasriSchool of Biological Sciences, Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA, 92093, USA.
Daniel J BroganSchool of Biological Sciences, Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA, 92093, USA.
Michelle BuiSchool of Biological Sciences, Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA, 92093, USA.
Ting YangSchool of Biological Sciences, Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA, 92093, USA.
Ming LiSchool of Biological Sciences, Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA, 92093, USA.
Michael DunnCSIRO Health and Biosecurity, Australian Centre for Disease Preparedness, Geelong, VIC 3220, AU.
Melissa J KleinCSIRO Health and Biosecurity, Australian Centre for Disease Preparedness, Geelong, VIC 3220, AU.
Sarah JacksonCSIRO Health and Biosecurity, Australian Centre for Disease Preparedness, Geelong, VIC 3220, AU.
Kyle CatalanCSIRO Health and Biosecurity, Australian Centre for Disease Preparedness, Geelong, VIC 3220, AU.
Kim R BlasdellCSIRO Health and Biosecurity, Australian Centre for Disease Preparedness, Geelong, VIC 3220, AU.
Priscilla TngArthropod Genetics, The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK.
Igor AntoshechkinDivision of Biology and Biological Engineering (BBE), California Institute of Technology, Pasadena, CA, 91125, USA.
Luke S AlpheyArthropod Genetics, The Pirbright Institute, Ash Road, Pirbright GU24 0NF, UK.
Prasad N ParadkarCSIRO Health and Biosecurity, Australian Centre for Disease Preparedness, Geelong, VIC 3220, AU.
Omar S AkbariSchool of Biological Sciences, Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA, 92093, USA.
University of California San Diego · USAustralian Centre for Disease Preparedness · AUThe Pirbright Institute · GBCalifornia Institute of Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Escalating vector disease burdens pose significant global health risks, so innovative tools for targeting mosquitoes are critical. We engineered an antiviral strategy termed REAPER (v

Indexed as

Cas13dCRISPR/CasmosquitoesRNA-knockdown

Identifiers

PMID36747634
PMCPMC9900881
OpenAlexW4318305514

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.