Evidence map›Paper›PMID 36747624›Full record

ArticlebioRxiv : the preprint server for biology2023

Conformationally responsive dyes enable protein-adaptive differential scanning fluorimetry.

Taiasean Wu, Joshua C Yu, Arundhati Suresh, Zachary J Gale-Day, Matthew G Alteen, Amanda S Woo, Zoe Millbern, Oleta T Johnson, Emma C Carroll, Carrie L Partch and 4 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Taiasean WuDepartment of Pharmaceutical Chemistry, University of California San Francisco; San Francisco, CA, 94038, USA.
Joshua C YuDepartment of Pharmaceutical Chemistry, University of California San Francisco; San Francisco, CA, 94038, USA.
Arundhati SureshDepartment of Pharmaceutical Chemistry, University of California San Francisco; San Francisco, CA, 94038, USA.
Zachary J Gale-DayDepartment of Pharmaceutical Chemistry, University of California San Francisco; San Francisco, CA, 94038, USA.
Matthew G AlteenDepartment of Chemistry, Simon Fraser University; Burnaby, BC V5A 1S6, Canada.
Amanda S WooDepartment of Pharmaceutical Chemistry, University of California San Francisco; San Francisco, CA, 94038, USA.
Zoe MillbernDepartment of Textile Engineering, North Carolina State University; Raleigh, NC 27695, USA.
Oleta T JohnsonInstitute for Neurodegenerative Diseases, University of California, San Francisco; San Francisco, CA, 94038, USA.
Emma C CarrollInstitute for Neurodegenerative Diseases, University of California, San Francisco; San Francisco, CA, 94038, USA.
Carrie L PartchDepartment of Chemistry, University of California, Santa Cruz; Santa Cruz, CA, 95064, USA.
Denis FourchesDepartment of Textile Engineering, North Carolina State University; Raleigh, NC 27695, USA.
Nelson R VinuezaDepartment of Textile Engineering, North Carolina State University; Raleigh, NC 27695, USA.
David J VocadloDepartment of Chemistry, Simon Fraser University; Burnaby, BC V5A 1S6, Canada.
Jason E GestwickiDepartment of Pharmaceutical Chemistry, University of California San Francisco; San Francisco, CA, 94038, USA.

Funding

Targeting Viroporins and Coronavirus M ProteinU19AI171110 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Nevan J Krogan · 2022 to 2026
$103.4M
UCSF IRACDA Scholars ProgramK12GM081266 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Raymond M. Esquerra, HOLLY A. INGRAHAM · 2007 to 2026
$19.4M
Structures and mechanisms of circadian rhythms from cyanobacteria to humansR35GM141849 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI PARTCH, CARRIE L · 2021 to 2025
$4.6M
Exploring the structural basis for 24-hour timekeeping in mammalsR01GM107069 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI PARTCH, CARRIE L · 2013 to 2020
$3.2M
Function of hemolymph plasma proteins in insect immune responses (Equipment Supplement)R35GM141859 · NIGMS · KANSAS STATE UNIVERSITY · PI KANOST, MICHAEL R · 2021 to 2025
$2.0M
Atomic resolution analysis of timekeeping by a protein-based circadian clockR01GM121507 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI PARTCH, CARRIE L · 2017 to 2020
$1.8M
Differential Scanning Fluorimetry (DSF) Methods for Studying Protein StabilityR01GM141299 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GESTWICKI, JASON E · 2021 to 2024
$1.5M
Developing Tools to Probe DnaJB6 Dynamics in Spinobulbular Muscular AtrophyK99NS128717 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, OLETA TANITREA · 2022 to 2022
$119k
Molecular recognition of pathological tau fibril conformationsF32AG076281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CARROLL, EMMA C · 2022 to 2023
$99k
NIAID NIH HHS U19 AI171110NIA NIH HHS F32 AG076281NIGMS NIH HHS K12 GM081266NIGMS NIH HHS R01 GM107069NIGMS NIH HHS R01 GM121507NIGMS NIH HHS R01 GM141299NIGMS NIH HHS R35 GM141849NIGMS NIH HHS R35 GM141859NINDS NIH HHS K99 NS128717
6 · The paper itself

Abstract

Flexible

Identifiers

PMID36747624
PMCPMC9900766

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.