Evidence map›Paper›PMID 36747545›Full record

ArticleHeliyon2023

Characterization of aspartokinase double mutants using a combination of experiments and simulations.

Zhijie Chen, Yu Fu, Shimeng Liu, Xinyu Huang, Xiaoting Kong, Zhaojie Mao, Ning Hu, Fengxiang Zhang, Caijing Han

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhijie ChenSchool of Pharmaceutical Sciences, Tsinghua University, 100084, Beijing, China.
Yu FuSchool of Public Health, Weifang Medical University, Weifang, 261053, Shandong, China.
Shimeng LiuJiaxing Xinbeilai Biotechnology Co., Ltd, China.
Xinyu HuangSchool of Public Health, Weifang Medical University, Weifang, 261053, Shandong, China.
Xiaoting KongSchool of Public Health, Weifang Medical University, Weifang, 261053, Shandong, China.
Zhaojie MaoSchool of Public Health, Weifang Medical University, Weifang, 261053, Shandong, China.
Ning HuSchool of Public Health, Weifang Medical University, Weifang, 261053, Shandong, China.
Fengxiang ZhangSchool of Public Health, Weifang Medical University, Weifang, 261053, Shandong, China.
Caijing HanSchool of Public Health, Weifang Medical University, Weifang, 261053, Shandong, China.
Weifang Medical University · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspartokinase (AK) is synergistically suppressed by Thr and Lys in the

Indexed as

AspartokinaseDouble mutantMDMechanismMSTSite-directed mutation

Identifiers

PMID36747545
PMCPMC9898291
OpenAlexW4318320760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.