Evidence map›Paper›PMID 36747202›Full record

ReviewJournal of nanobiotechnology2023

Smart nanoparticles and microbeads for interventional embolization therapy of liver cancer: state of the art.

Sitong Wu, Kevin Fan, Qi Yang, Zhao Chen, Yi Hou, Yinghua Zou, Weibo Cai, Lei Kang

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sitong WuDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, 100034, China.
Kevin FanDepartments of Radiology and Medical Physics, University of Wisconsin, Madison, WI, 53705, USA.
Qi YangDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, 100034, China.
Zhao ChenDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, 100034, China.
Yi HouCollege of Life Science and Technology, Beijing University of Chemical Technology, Beijing, 100029, China. houyi@iccas.ac.cn.
Yinghua ZouDepartment of Interventional Radiology and Vascular Surgery, Peking University First Hospital, Beijing, 100034, China. pkuzouyhua@163.com.
Weibo CaiDepartments of Radiology and Medical Physics, University of Wisconsin, Madison, WI, 53705, USA. wcai@uwhealth.org.
Lei KangDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, 100034, China. kanglei@bjmu.edu.cn.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
NCI NIH HHS P30 CA014520
6 · The paper itself

Abstract

The process of transcatheter arterial chemoembolization is characterized by the ability to accurately deliver chemotherapy drugs with minimal systemic side effects and has become the standard treatment for unresectable intermediate hepatocellular carcinoma (HCC). However, this treatment option still has much room for improvement, one of which may be the introduction of nanomaterials, which exhibit unique functions and can be applied to in vivo tumor imaging and therapy. Several biodegradable and multifunctional nanomaterials and nanobeads have recently been developed and applied in the locoregional treatment of hepatocellular cancer. This review explores recent developments and findings in relation to micro-nano medicines in transarterial therapy for HCC, emerging strategies to improve the efficacy of delivering nano-based medicines, and expounding prospects for clinical applications of nanomaterials.

Indexed as

Carcinoma, HepatocellularChemoembolization, TherapeuticLiver NeoplasmsNanoparticlesHumansMicrospheresDegradableHepatocellular carcinomaMicrospheresMultifunctionalNanoparticlesTransarterial chemoembolization

Identifiers

PMID36747202
PMCPMC9901004

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.