Evidence map›Paper›PMID 36747123›Full record

ArticleBMC cardiovascular disorders2023

Bayesian networks identify determinants of outcomes following cardiac surgery in a UK population.

Khurum Mazhar, Saifullah Mohamed, Akshay J Patel, Sarah Berger Veith, Giles Roberts, Richard Warwick, Lognathen Balacumaraswami, Qamar Abid, Marko Raseta

Abstract read
In one paragraph

Article in BMC cardiovascular disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Khurum MazharRoyal Stoke University Hospital, Stoke on Trent, UK.
Saifullah MohamedRoyal Stoke University Hospital, Stoke on Trent, UK.
Akshay J PatelInstitute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. ajp.788@gmail.com.
Sarah Berger VeithFaculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany.
Giles RobertsRoyal Stoke University Hospital, Stoke on Trent, UK.
Richard WarwickRoyal Stoke University Hospital, Stoke on Trent, UK.
Lognathen BalacumaraswamiRoyal Stoke University Hospital, Stoke on Trent, UK.
Qamar AbidRoyal Stoke University Hospital, Stoke on Trent, UK.
Marko RasetaRoyal Stoke University Hospital, Stoke on Trent, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraditional risk stratification tools do not describe the complex principle determinant relationships that exist amongst pre-operative and peri-operative factors and their influence on cardiac surgical outcomes. This paper reports on the use of Bayesian networks to investigate such outcomes.

methodsData were prospectively collected from 4776 adult patients undergoing cardiac surgery at a single UK institute between April 2012 and May 2019. Machine learning techniques were used to construct Bayesian networks for four key short-term outcomes including death, stroke and renal failure.

resultsDuration of operation was the most important determinant of death irrespective of EuroSCORE. Duration of cardiopulmonary bypass was the most important determinant of re-operation for bleeding. EuroSCORE was predictive of new renal replacement therapy but not mortality.

conclusionsMachine-learning algorithms have allowed us to analyse the significance of dynamic processes that occur between pre-operative and peri-operative elements. Length of procedure and duration of cardiopulmonary bypass predicted mortality and morbidity in patients undergoing cardiac surgery in the UK. Bayesian networks can be used to explore potential principle determinant mechanisms underlying outcomes and be used to help develop future risk models.

Indexed as

Cardiac Surgical ProceduresRenal InsufficiencyAdultBayes TheoremCardiopulmonary BypassHumansRisk AssessmentRisk FactorsUnited KingdomBayesian networkCardiac surgeryEuroSCOREOutcomesRisk stratification

Identifiers

PMID36747123
PMCPMC9903419

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.