ArticleNature chemical biology2023
Complex regulation in a Comamonas platform for diverse aromatic carbon metabolism.
Article in Nature chemical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 79 citations in OpenAlex.
- Exploring the native pulp and paper sludge microbiome to inspire new biotechnologies for waste minimization.Microbiology spectrum · 2026Article
- Diverse Microbial Communities Assemble on Both Recalcitrant and Labile Carbon Sources.Environmental microbiology · 2026Article
- Engineering a robust and autonomous biological funneling for efficient valorization of lignin-related aromatics.Nature communications · 2026Article
- Biofiltration of Emerging Contaminants as a Sustainable Pest Management Strategy and Its Impact onPharmaceuticals (Basel, Switzerland) · 2026Article
- Mitigating protocatechuic acid toxicity in Vibrio natriegens enables poly-3-hydroxybutyrate production from an aromatic carbon source.Applied microbiology and biotechnology · 2026Article
- Biochemical Upcycling of PET via Glycolysis and Engineered Microbial Consortia.Microbial biotechnology · 2026Article
- Genetically encoded biosensor enabled mining, characterisation and engineering of aromatic acid MFS transporters.Journal of biological engineering · 2025Article
- It Is Dangerous to Go Alone: Strategies to Optimize PET Biocatalysis and Upcycling through Enzymatic Synergism.ACS omega · 2025Review
- Quantitative decoding of coupled carbon and energy metabolism in Pseudomonas putida for lignin carbon utilization.Communications biology · 2025Article
- High enzyme promiscuity in lignin degradation mechanisms inApplied and environmental microbiology · 2025Article
- Lignin-Degrading Enzymes and the Potential ofMicroorganisms · 2025Review
- Microbial metabolism of host-derived antioxidants.Current opinion in chemical biology · 2025Review
- Surfing in the storm: how Paraburkholderia xenovorans thrives under stress during biodegradation of toxic aromatic compounds and other stressors.FEMS microbiology reviews · 2025Review
- Addressing genome scale design tradeoffs in Pseudomonas putida for bioconversion of an aromatic carbon source.NPJ systems biology and applications · 2025Article
- Plastic degradation by enzymes from uncultured deep sea microorganisms.The ISME journal · 2025Article
- Environmental Impact of Xenobiotic Aromatic Compounds and Their Biodegradation Potential inInternational journal of molecular sciences · 2024Review
- Biodegradation of phthalic acid and terephthalic acid by Comamonas testosteroni strains.Folia microbiologica · 2024Article
- Comparative genomic analysis and characterization of novel high-quality draft genomes from the coal metagenome.World journal of microbiology & biotechnology · 2024Article
- Mechanisms of Polyethylene Terephthalate Pellet Fragmentation into Nanoplastics and Assimilable Carbons by WastewaterEnvironmental science & technology · 2024Article
- Impact of a Potent Strain of Plant Growth-Promoting Bacteria (PGPB), Bacillus subtilis S1 on Bacterial Community Composition, Enzymatic Activity, and Nitrogen Content in Cucumber Rhizosphere Soils.Current microbiology · 2024Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Critical to a sustainable energy future are microbial platforms that can process aromatic carbons from the largely untapped reservoir of lignin and plastic feedstocks. Comamonas species present promising bacterial candidates for such platforms because they can use a range of natural and xenobiotic aromatic compounds and often possess innate genetic constraints that avoid competition with sugars. However, the metabolic reactions of these species are underexplored, and the regulatory mechanisms are unknown. Here we identify multilevel regulation in the conversion of lignin-related natural aromatic compounds, 4-hydroxybenzoate and vanillate, and the plastics-related xenobiotic aromatic compound, terephthalate, in Comamonas testosteroni KF-1. Transcription-level regulation controls initial catabolism and cleavage, but metabolite-level thermodynamic regulation governs fluxes in central carbon metabolism. Quantitative
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.