Evidence map›Paper›PMID 36746986›Full record

Observational studyJournal of perinatology : official journal of the California Perinatal Association2023

Comparing maternal substance use and perinatal outcomes before and during the COVID-19 pandemic.

Joan Lien, Tristan Hayes, Feng Liu-Smith, Divya Rana

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joan LienDepartment of Pediatrics, University of Tennessee Health Sciences Center, Memphis, TN, USA. joan-lien@ouhsc.edu.ORCID 0000-0001-7140-4123
Tristan HayesDivision of Biostatistics, Department of Preventive Medicine, University of Tennessee Health Sciences Center, Memphis, TN, USA.
Feng Liu-SmithDivision of Epidemiology, Department of Preventive Medicine, University of Tennessee Health Sciences Center, Memphis, TN, USA.ORCID 0000-0003-3963-0651
Divya RanaDivision of Neonatology, Department of Pediatrics, University of Tennessee Health Sciences Center, Memphis, TN, USA.ORCID 0000-0002-3720-9495
University of Tennessee Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the effect of the COVID-19 pandemic on maternal substance abuse and neonatal outcomes. STUDY

designCross-sectional observational study of neonates admitted to the NICU and born to mothers with evidence of substance abuse pre-pandemic compared to during the COVID-19 pandemic.

resultWe noted a significant increase in fentanyl (12% vs. 0.6%, p < 0.001) and tobacco use (64% vs. 33%, p < 0.001) during the pandemic compared to pre-pandemic, including an increase in fentanyl use among mothers enrolled in opioid maintenance therapy (OMT) during the pandemic (32.3% vs. 1.5%, p < 0.001). There was a significant increase in preterm births (58% vs. 48%, p = 0.022) and lower birth weight (2315 ± 815 vs. 2455 ± 861 g, p = 0.049) during pandemic.

conclusionThere was a significant increase in maternal fentanyl use during the pandemic, even with OMT enrollment, with an increase in preterm births and lower birth weights among infants born to mothers with substance use.

Indexed as

COVID-19Premature BirthSubstance-Related DisordersBirth WeightCross-Sectional StudiesFemaleFentanylHumansInfantInfant, NewbornPandemicsPregnancyFentanyl

Identifiers

PMID36746986
PMCPMC9901406
OpenAlexW4319296139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.