ArticleNature communications2023
DNA-Aeon provides flexible arithmetic coding for constraint adherence and error correction in DNA storage.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed.
- Towards density-optimal DNA storage with practical bijective coding.Nature communications · 2026Article
- A DNA-Local, Constraint-Aware Dual-Head Transformer for Pseudorandom Stream Generation.Entropy (Basel, Switzerland) · 2026Article
- Highly biased DNA sequence reconstruction in DNA storage with multi-scale attention mechanism and contrast learning.Synthetic and systems biotechnology · 2026Article
- Gungnir codec enabling high error-tolerance and low-redundancy DNA storage through substantial computing power.Nature communications · 2026Article
- Comparison of state-of-the-art error-correction coding for sequence-based DNA data storage.Nature communications · 2026Article
- Quantitative Assessment of Randomized DNA Base Sequences Using Multi-Model Physical Analysis for High-Fidelity Data Storage.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- DNA conjugation on functionalized plastic surfaces for sequential, iterative single molecule sequencing.Scientific reports · 2026Article
- Two-dimensional data storage using a DNA molecular register.Frontiers in bioengineering and biotechnology · 2026Article
- DNA StairLoop: enabling high-fidelity data recovery and robust error correction in DNA-based data storage.Nature communications · 2025Article
- Achieving handle-level random access in an encrypted DNA archival storage system via frequency dictionary mapping coding.Patterns (New York, N.Y.) · 2025Article
- Predict the degree of secondary structures of the encoding sequences in DNA storage by deep learning model.Scientific reports · 2025Article
- Sequence analysis and decoding with extra low-quality reads for DNA data storage.Bioinformatics (Oxford, England) · 2025Article
- DNA storage: The future direction for medical cold data storage.Synthetic and systems biotechnology · 2025Review
- Cost-Effective DNA Storage System with DNA Movable Type.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- DNA palette code for time-series archival data storage.National science review · 2025Article
- INNSE: Invertible neural network-based DNA image storage with self-correction encoding.Computational and structural biotechnology journal · 2025Article
- Optimizing fountain codes for DNA data storage.Computational and structural biotechnology journal · 2024Article
- Data recovery methods for DNA storage based on fountain codes.Computational and structural biotechnology journal · 2024Article
- Composite Hedges Nanopores codec system for rapid and portable DNA data readout with high INDEL-Correction.Nature communications · 2024Article
- Efficient and low-complexity variable-to-variable length coding for DNA storage.BMC bioinformatics · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The extensive information capacity of DNA, coupled with decreasing costs for DNA synthesis and sequencing, makes DNA an attractive alternative to traditional data storage. The processes of writing, storing, and reading DNA exhibit specific error profiles and constraints DNA sequences have to adhere to. We present DNA-Aeon, a concatenated coding scheme for DNA data storage. It supports the generation of variable-sized encoded sequences with a user-defined Guanine-Cytosine (GC) content, homopolymer length limitation, and the avoidance of undesired motifs. It further enables users to provide custom codebooks adhering to further constraints. DNA-Aeon can correct substitution errors, insertions, deletions, and the loss of whole DNA strands. Comparisons with other codes show better error-correction capabilities of DNA-Aeon at similar redundancy levels with decreased DNA synthesis costs. In-vitro tests indicate high reliability of DNA-Aeon even in the case of skewed sequencing read distributions and high read-dropout.
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