Evidence map›Paper›PMID 36746872›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2023

Effects of Euterpe oleracea Mart. extract on Candida spp. biofilms.

Larissa Lira Brito, Kátia Regina Assunção Borges, Gabriel Xavier Silva, Marcos Antonio Custódio Neto da Silva, Rita de Nazaré Silva Alves, Amanda Mara Teles, Maria do Carmo Lacerda Barbosa, Walbert Edson Muniz Filho, Geusa Felipa de Barros Bezerra, Maria do Desterro Soares Brandão Nascimento

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Larissa Lira BritoPostgraduate Program in Adult Health, Federal University of Maranhão, Av. Dos Portugueses, 1966, Bacanga, São Luís, MA, 65080-805, Brazil.
Kátia Regina Assunção BorgesPostgraduate Program in Adult Health, Federal University of Maranhão, Av. Dos Portugueses, 1966, Bacanga, São Luís, MA, 65080-805, Brazil.
Gabriel Xavier SilvaNucleum of Basic and Applied Immunology, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Marcos Antonio Custódio Neto da SilvaPostgraduate Program in Internal Medicine, University of Campinas, Campinas, São Paulo, Brazil.
Rita de Nazaré Silva AlvesPostgraduate Program in Adult Health, Federal University of Maranhão, Av. Dos Portugueses, 1966, Bacanga, São Luís, MA, 65080-805, Brazil.
Amanda Mara TelesNucleum of Basic and Applied Immunology, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Maria do Carmo Lacerda BarbosaNucleum of Basic and Applied Immunology, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Walbert Edson Muniz FilhoNucleum of Basic and Applied Immunology, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Geusa Felipa de Barros BezerraPostgraduate Program in Adult Health, Federal University of Maranhão, Av. Dos Portugueses, 1966, Bacanga, São Luís, MA, 65080-805, Brazil.
Maria do Desterro Soares Brandão NascimentoPostgraduate Program in Adult Health, Federal University of Maranhão, Av. Dos Portugueses, 1966, Bacanga, São Luís, MA, 65080-805, Brazil. m.desterro.soares@gmail.com.ORCID http://orcid.org/0000-0003-2783-362X
Universidade Federal do Maranhão · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão 031/2016
6 · The paper itself

Abstract

problem of researchCandida spp. biofilms are complex microbial communities that have been associated with increasing resistance to clinically available antifungal drugs. Hence, novel pharmacological approaches with ability to inhibit biofilm formation have been investigated. AIM OF STUDY: The aim was to analyze in vitro antifungal activity of Euterpe oleracea Mart. (açaí berry) extract on biofilm strains of Candida albicans, C. parapsilosis, and C. tropicalis that were formed on abiotic surfaces. REMARKABLE METHODOLOGY: Biofilms of C. albicans, C. parapsilosis, and C. tropicalis were grown in vitro. They were then treated with E. oleracea Mart. extract at different concentrations (7.8, 15.6, 31.2, 62.5, 125, 250, 500, and 1000 μg/mL) for evaluation of both biofilm removal and anti-biofilm activity. REMARKABLE

resultsAll Candida species analyzed formed biofilms on abiotic surfaces. Yet, increased biofilm formation was displayed for C. tropicalis in comparison with the other two species. E. oleracea Mart. extract was shown to inhibit biofilm formation at all concentrations used when compared to no treatment (p < 0.05). SIGNIFICANCE OF THE STUDY: In the current study, the extract of E. oleracea Mart. demonstrated antifungal activity against Candida albicans, C. parapsilosis, and C. tropicalis biofilms, regardless of the dose utilized. These results are important to evaluate a natural product as antifungal for Candida species.

Indexed as

CandidaEuterpeAntifungal AgentsBiofilmsCandida albicansCandida parapsilosisCandida tropicalisMicrobial Sensitivity TestsPlant ExtractsAntifungal AgentsPlant ExtractsAntifungal activityBiofilmsCandidaEuterpe oleracea

Identifiers

PMID36746872
PMCPMC9944593
OpenAlexW4319334458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.