Evidence map›Paper›PMID 36746835›Full record

ArticleJournal of natural medicines2023

Eumitrins I-K: three new xanthone dimers from the lichen Usnea baileyi.

Van-Kieu Nguyen, Phan-Si-Nguyen Dong, Hoai-Vu Nguyen-Si, Ek Sangvichien, Thanh-Nha Tran, Le-Thuy-Thuy-Trang Hoang, Minh-Trung Dao, Hai-Nguyen, Hoang-Vinh-Truong Phan, Hioki Yusuke and 2 more

Abstract read
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Article in Journal of natural medicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Van-Kieu NguyenInstitute of Fundamental and Applied Sciences, Duy Tan University, Ho Chi Minh City, Vietnam. nguyenvankieu2@duytan.edu.vn.ORCID http://orcid.org/0000-0001-9623-2735
Phan-Si-Nguyen DongInstitute of Fundamental and Applied Sciences, Duy Tan University, Ho Chi Minh City, Vietnam.
Hoai-Vu Nguyen-SiInstitute of Fundamental and Applied Sciences, Duy Tan University, Ho Chi Minh City, Vietnam.
Ek SangvichienLichen Research Unit and Lichen Herbarium, Department of Biology, Faculty of Science, Ramkhamhaeng University, Bangkapi, Bangkok, 10240, Thailand.
Thanh-Nha TranDepartment of Environmental Engineering, Thu Dau Mot University, Binh Duong, Vietnam.
Le-Thuy-Thuy-Trang HoangDepartment of Environmental Engineering, Thu Dau Mot University, Binh Duong, Vietnam.
Minh-Trung DaoDepartment of Environmental Engineering, Thu Dau Mot University, Binh Duong, Vietnam.
Hai-NguyenInstitute of Fundamental and Applied Sciences, Duy Tan University, Ho Chi Minh City, Vietnam.
Hoang-Vinh-Truong PhanInstitute of Fundamental and Applied Sciences, Duy Tan University, Ho Chi Minh City, Vietnam.
Hioki YusukeGraduate School of Natural Science and Technology, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.
Tohru MitsunagaFaculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.
Warinthorn ChavasiriCenter of Excellence in Natural Products Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand. warinthorn.c@chula.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the continuing discovery and structure elucidation of natural xanthone dimers, which are still rarely reported in absolute configuration, three new xanthone dimers, eumitrins I-K (1-3) were isolated from the lichen Usnea baileyi, a rich source of natural xanthone dimers. Their structures were elucidated unambiguously by spectroscopic analyses, including high-resolution electrospray ionization mass spectrometry (HRESIMS), 1D and 2D nuclear magnetic resonance spectroscopy (1D and 2D NMR). The absolute configuration of all three compounds was established through DP4 probability and ECD calculation. All compounds revealed weak activity for their enzymatic inhibition against α-glucosidase and tyrosinase, as well as antibacterial activity.

Indexed as

LichensXanthonesAscomycotaMolecular StructureParmeliaceaeXanthonesAntibacterialDimeric xanthoneEnzyme inhibitoryLichenUsnea baileyiα-Glucosidase

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.