ArticleBiochemistry2023
H-NOX Regulates Biofilm Formation in
Dominique E Williams, Natasha M Nesbitt, Sandhya Muralidharan, Sajjad Hossain, Elizabeth M Boon
Open access · greenAbstract read
In one paragraphArticle in Biochemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 1 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
5 authors at 1 institution in 1 country.
Dominique E WilliamsDepartment of Chemistry and Institute of Chemical Biology and Drug Design, Stony Brook University, Stony Brook, New York 11794-3400, United States.
Natasha M NesbittDepartment of Chemistry and Institute of Chemical Biology and Drug Design, Stony Brook University, Stony Brook, New York 11794-3400, United States.
Sandhya MuralidharanDepartment of Chemistry and Institute of Chemical Biology and Drug Design, Stony Brook University, Stony Brook, New York 11794-3400, United States.
Sajjad HossainDepartment of Chemistry and Institute of Chemical Biology and Drug Design, Stony Brook University, Stony Brook, New York 11794-3400, United States.
Elizabeth M BoonDepartment of Chemistry and Institute of Chemical Biology and Drug Design, Stony Brook University, Stony Brook, New York 11794-3400, United States.ORCID 0000-0003-1891-839X Stony Brook University · US
Funding
IRACDA - The New York Consortium for the Advancement of Postdoctoral Scholars (NY CAPS)Phase IIK12GM102778 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI Carol A. Carter, Karian Janice Wright · 2012 to 2026
$13.1MThe role of NosP in Pseudomonas aeruginosa biofilm developmentR01GM118894 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI ELIZABETH M BOON · 2017 to 2026
$3.0MChemical Biology Training InterfaceT32GM136572 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI ELIZABETH M BOON, Jessica Chuang Seeliger · 2020 to 2026
$2.9MNIGMS NIH HHS K12 GM102778NIGMS NIH HHS R01 GM118894NIGMS NIH HHS T32 GM136572
6 · The paper itselfAbstract
Transitions between motile and biofilm lifestyles are highly regulated and fundamental to microbial pathogenesis. H-NOX (heme-nitric oxide/oxygen-binding domain) is a key regulator of bacterial communal behaviors, such as biofilm formation. A predicted bifunctional cyclic di-GMP metabolizing enzyme, composed of diguanylate cyclase and phosphodiesterase (PDE) domains (
Indexed as
Bacterial ProteinsEscherichia coli ProteinsAgrobacteriumBiofilmsCyclic GMPGene Expression Regulation, BacterialKineticsNitric OxidePhosphorus-Oxygen LyasesBacterial ProteinsCyclic GMPEscherichia coli ProteinsNitric OxidePhosphorus-Oxygen Lyases
Identifiers
PMID36746768
PMCPMC10332389
OpenAlexW4319299122
What OpenQuestion holds
Textmetadata
LicenceTDM
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